Study of Radioactive Progeny Recoils Release from 225Ac Labelled TiO2 Nanoparticles
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21340%2F22%3A00365031" target="_blank" >RIV/68407700:21340/22:00365031 - isvavai.cz</a>
Výsledek na webu
<a href="https://link.springer.com/article/10.1007/s00259-022-05924-4" target="_blank" >https://link.springer.com/article/10.1007/s00259-022-05924-4</a>
DOI - Digital Object Identifier
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Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Study of Radioactive Progeny Recoils Release from 225Ac Labelled TiO2 Nanoparticles
Popis výsledku v původním jazyce
Targeted alpha therapy (TAT) plays important role in palliative as well as curative treatment of patients with oncological diseases. Several radionuclides suitable for TAT are decay by emission of α-particle cascade, which can on one hand improve therapeutic outcome, but on the other hand also cause severe damage to non-target tissues. One strategy to least partially reduce this progeny spread over the body is based on the use of nanoparticles (NPs) [2]. The aim of this work was to determine the fraction of recoiling atoms activity originating from 225Ac decay (221Fr, 213Bi) and study the progeny wash-out dependence over time and on the concentration of TiO2 NPs as a potential carrier of radionuclides for TAT.
Název v anglickém jazyce
Study of Radioactive Progeny Recoils Release from 225Ac Labelled TiO2 Nanoparticles
Popis výsledku anglicky
Targeted alpha therapy (TAT) plays important role in palliative as well as curative treatment of patients with oncological diseases. Several radionuclides suitable for TAT are decay by emission of α-particle cascade, which can on one hand improve therapeutic outcome, but on the other hand also cause severe damage to non-target tissues. One strategy to least partially reduce this progeny spread over the body is based on the use of nanoparticles (NPs) [2]. The aim of this work was to determine the fraction of recoiling atoms activity originating from 225Ac decay (221Fr, 213Bi) and study the progeny wash-out dependence over time and on the concentration of TiO2 NPs as a potential carrier of radionuclides for TAT.
Klasifikace
Druh
O - Ostatní výsledky
CEP obor
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OECD FORD obor
10402 - Inorganic and nuclear chemistry
Návaznosti výsledku
Projekt
<a href="/cs/project/TJ04000129" target="_blank" >TJ04000129: Separace radionuklidů pro cílenou alfa částicovou terapii</a><br>
Návaznosti
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Ostatní
Rok uplatnění
2022
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů