Geometry Optimization of Idealized Total Cavopulmonary Connection Using a CFD-Based Framework

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21340%2F25%3A00386245" target="_blank" >RIV/68407700:21340/25:00386245 - isvavai.cz</a>

Výsledek na webu

<a href="https://doi.org/10.1007/978-3-031-94562-5_36" target="_blank" >https://doi.org/10.1007/978-3-031-94562-5_36</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/978-3-031-94562-5_36" target="_blank" >10.1007/978-3-031-94562-5_36</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Geometry Optimization of Idealized Total Cavopulmonary Connection Using a CFD-Based Framework

Popis výsledku v původním jazyce

A computational fluid dynamics-based framework for optimizing 3D geometry in an idealized total cavopulmonary connection (TCPC) is presented. The TCPC is a surgical procedure designed to treat congenital heart defects involving a single functional ventricle. The presented custom optimization framework integrates Python-based geometry generation, lattice Boltzmann method (LBM) simulations, and gradient-free optimization algorithms, including Nelder-Mead and the Mesh Adaptive Direct Search methods. The three optimization steps generation of parameterized 3D geometry, simulation of incompressible Newtonian fluid flow with a rigid wall, and evaluation of objective functions - are executed automatically. The massively parallel implementation of LBM on GPUs allows the use of a spatial resolution suitable for optimizing the flow metrics sensitive to the actual resolution, such as the turbulent kinetic energy or near-wall shear rate. A simplified, parameterized model of the TCPC geometry was used to test the framework, demonstrating its feasibility and effectiveness. While this study focuses on idealized geometries with simplified assumptions, the results provide a foundation for extending the framework to patient-specific data and more complex physiological scenarios. This work represents a step in applying computational optimization to cardiovascular surgery, with the potential to improve clinical outcomes and patient-specific treatment planning.

Název v anglickém jazyce

Geometry Optimization of Idealized Total Cavopulmonary Connection Using a CFD-Based Framework

Popis výsledku anglicky

A computational fluid dynamics-based framework for optimizing 3D geometry in an idealized total cavopulmonary connection (TCPC) is presented. The TCPC is a surgical procedure designed to treat congenital heart defects involving a single functional ventricle. The presented custom optimization framework integrates Python-based geometry generation, lattice Boltzmann method (LBM) simulations, and gradient-free optimization algorithms, including Nelder-Mead and the Mesh Adaptive Direct Search methods. The three optimization steps generation of parameterized 3D geometry, simulation of incompressible Newtonian fluid flow with a rigid wall, and evaluation of objective functions - are executed automatically. The massively parallel implementation of LBM on GPUs allows the use of a spatial resolution suitable for optimizing the flow metrics sensitive to the actual resolution, such as the turbulent kinetic energy or near-wall shear rate. A simplified, parameterized model of the TCPC geometry was used to test the framework, demonstrating its feasibility and effectiveness. While this study focuses on idealized geometries with simplified assumptions, the results provide a foundation for extending the framework to patient-specific data and more complex physiological scenarios. This work represents a step in applying computational optimization to cardiovascular surgery, with the potential to improve clinical outcomes and patient-specific treatment planning.

Druh

D - Stať ve sborníku

CEP obor

—

OECD FORD obor

10102 - Applied mathematics

Projekt

<a href="/cs/project/LUAUS25049" target="_blank" >LUAUS25049: Translace matematického modelování a optimalizačních technik do kardiovaskulární medicíny</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2025

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název statě ve sborníku

Functional Imaging and Modeling of the Heart

ISBN

978-3-031-94558-8

ISSN

0302-9743

e-ISSN

1611-3349

Počet stran výsledku

10

Strana od-do

397-406

Název nakladatele

Springer Nature Publishing AG

Místo vydání

Cham

Místo konání akce

Dallas

Datum konání akce

1. 6. 2025

Typ akce podle státní příslušnosti

WRD - Celosvětová akce

Kód UT WoS článku

001527426700036