Vliv krystalihity na biofyzikální vlastnosti tenkých vrstev hydroxyapatitu

Kód výsledku v IS VaVaI

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Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Influence of crystallinity on bio-physical properties of hydroxapatite films

Popis výsledku v původním jazyce

Crystalline and amorphous hydroxapatite (HA) films were prepared by KrF pulsed laser deposition method. Influence of HA structure on biomedical properties was studied. Crystallinity, morphology, composition, optical transmission and mechanical properties(adhesion) were measured. Biomedical properties were tested using human dermal fibroblast. The specific proteins (vimentin, fibronectin, pankeratin, keratin 14) were visualized. The worst proliferation of fibroblasts was observed on the amophous coating, whereas the adhesion was well comparable with other surfaces. The level of keratinocyte differentiation on the amorphous and crystalline HA coating was the same. Results reached on physical and mechanical properties are discussed in connection with results of in vitro tests.

Název v anglickém jazyce

Influence of crystallinity on bio-physical properties of hydroxapatite films

Popis výsledku anglicky

Crystalline and amorphous hydroxapatite (HA) films were prepared by KrF pulsed laser deposition method. Influence of HA structure on biomedical properties was studied. Crystallinity, morphology, composition, optical transmission and mechanical properties(adhesion) were measured. Biomedical properties were tested using human dermal fibroblast. The specific proteins (vimentin, fibronectin, pankeratin, keratin 14) were visualized. The worst proliferation of fibroblasts was observed on the amophous coating, whereas the adhesion was well comparable with other surfaces. The level of keratinocyte differentiation on the amorphous and crystalline HA coating was the same. Results reached on physical and mechanical properties are discussed in connection with results of in vitro tests.

Druh

D - Stať ve sborníku

CEP obor

BH - Optika, masery a lasery

OECD FORD obor

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Projekt

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Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2008

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název statě ve sborníku

4th Kuala Lumpur International Conference on Biomedical Engineering

ISBN

978-3-540-69139-6

ISSN

1680-0737

e-ISSN

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Počet stran výsledku

3

Strana od-do

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Název nakladatele

Springer

Místo vydání

Heidelberg

Místo konání akce

Kuala Lumpur

Datum konání akce

25. 6. 2008

Typ akce podle státní příslušnosti

WRD - Celosvětová akce

Kód UT WoS článku

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