Characterization of colonic microbial community in patients with Alzheimer's disease

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21460%2F12%3A00202757" target="_blank" >RIV/68407700:21460/12:00202757 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Characterization of colonic microbial community in patients with Alzheimer's disease

Popis výsledku v původním jazyce

Alzheimer's disease is one of the major neurodegenerative diseases; the elderly population is affected (about 50% at age 85 years). Manifested by memory loss, impairedspeech and worsening of orientation change of personality. According to some research on the emergence and development of the involved metabolites produced in the digestive tract, resulting in a hypothesis concerning the proportion of microbial activity in the etiology of this disease. Comparison of faecal microflora composition differences in healthy people and patients should contribude to understanding the etiology and pathogenesis of the disease. Real Time PCR was used to monitor possible changes in the levels of total bacteria and the levels of individual bacterial groups: Bifidobacteria, Clostridium leptum, Enterobacteriaceae, Lactobacillus- Streptococcus-Enterobacter, and Bacteroides- Prevotella. The DGGE profiles revealed the great complexity and specificity of eachtest subjects and changes in the composition of s

Název v anglickém jazyce

Characterization of colonic microbial community in patients with Alzheimer's disease

Popis výsledku anglicky

Alzheimer's disease is one of the major neurodegenerative diseases; the elderly population is affected (about 50% at age 85 years). Manifested by memory loss, impairedspeech and worsening of orientation change of personality. According to some research on the emergence and development of the involved metabolites produced in the digestive tract, resulting in a hypothesis concerning the proportion of microbial activity in the etiology of this disease. Comparison of faecal microflora composition differences in healthy people and patients should contribude to understanding the etiology and pathogenesis of the disease. Real Time PCR was used to monitor possible changes in the levels of total bacteria and the levels of individual bacterial groups: Bifidobacteria, Clostridium leptum, Enterobacteriaceae, Lactobacillus- Streptococcus-Enterobacter, and Bacteroides- Prevotella. The DGGE profiles revealed the great complexity and specificity of eachtest subjects and changes in the composition of s

Druh

D - Stať ve sborníku

CEP obor

EE - Mikrobiologie, virologie

OECD FORD obor

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Projekt

<a href="/cs/project/EE.2.3.20.0092" target="_blank" >EE.2.3.20.0092: Rozvoj výzkumného týmu BIO-OPT-XUV na FBMI ČVUT</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2012

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název statě ve sborníku

Instuments and Methods for Biology and Medicine 2012

ISBN

978-80-01-05119-1

ISSN

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e-ISSN

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Počet stran výsledku

3

Strana od-do

39-41

Název nakladatele

Czech Technical University

Místo vydání

Prague

Místo konání akce

Kladno

Datum konání akce

29. 5. 2012

Typ akce podle státní příslušnosti

CST - Celostátní akce

Kód UT WoS článku

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