Interactions of nitrogen?vacancy centers with charged surfaces of functionalized nanodiamond particles for the detection of cellular processes

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21460%2F13%3A00207033" target="_blank" >RIV/68407700:21460/13:00207033 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Interactions of nitrogen?vacancy centers with charged surfaces of functionalized nanodiamond particles for the detection of cellular processes

Popis výsledku v původním jazyce

This doctoral thesis presents the study of optical properties of nitrogen-vacancy (NV) centers in variously functionalized fluorescent nanodiamond particles (FND). NV center in diamond is a deep laying point defect which is the diamond bandgap, containing nitrogen and a neighboring vacancy. In this thesis we used the very specific properties of these NV centers engineered in diamond to be used as nanoscale sensors operating in cells. High biocompatibility of nanodiamond, variable FND size ranging from ~5 nm, stable luminescence from its NV centers and simple carbon chemistry for biomolecule grafting make FND an attractive alternative to molecular dyes for drug-delivery. This thesis present a principle of a novel method that can be used for remote monitoring of chemical processes in biological environment based on color changes from photo-luminescent (PL) NV centers in FND. It is proposed to drive the NV luminescence chemically, by alternating the surface chemical potential by interact

Název v anglickém jazyce

Interactions of nitrogen?vacancy centers with charged surfaces of functionalized nanodiamond particles for the detection of cellular processes

Popis výsledku anglicky

This doctoral thesis presents the study of optical properties of nitrogen-vacancy (NV) centers in variously functionalized fluorescent nanodiamond particles (FND). NV center in diamond is a deep laying point defect which is the diamond bandgap, containing nitrogen and a neighboring vacancy. In this thesis we used the very specific properties of these NV centers engineered in diamond to be used as nanoscale sensors operating in cells. High biocompatibility of nanodiamond, variable FND size ranging from ~5 nm, stable luminescence from its NV centers and simple carbon chemistry for biomolecule grafting make FND an attractive alternative to molecular dyes for drug-delivery. This thesis present a principle of a novel method that can be used for remote monitoring of chemical processes in biological environment based on color changes from photo-luminescent (PL) NV centers in FND. It is proposed to drive the NV luminescence chemically, by alternating the surface chemical potential by interact

Druh

O - Ostatní výsledky

CEP obor

BO - Biofyzika

OECD FORD obor

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Projekt

<a href="/cs/project/EE2.3.20.0306" target="_blank" >EE2.3.20.0306: Integrace týmu pro vývoj a výzkum nových principů nanotechnologie v biomedicíně pro vzdělávání a lékařskou praxi</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2013

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů