Evaluation of movement of patients with Parkinson's disease using accelerometers and method based on eigenvectors

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21460%2F16%3A00316718" target="_blank" >RIV/68407700:21460/16:00316718 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Evaluation of movement of patients with Parkinson's disease using accelerometers and method based on eigenvectors

Popis výsledku v původním jazyce

The article focuses on a technique of quantifying movement of patients with Parkinson's disease (PD) using accelerometers and method based on eigenvectors. The method uses trend symmetry to compare acceleration's waveforms of left and right side of body. The trend symmetry value is calculated as a ratio of the variabilities of two eigenvectors, which are calculated from the kinematic motion data of left and right limb. The method utilizes eigenvectors of matrices of accelerations to compare time-normalized right leg and left leg gait cycles of patients and healthy subjects. Four accelerometers were placed on patient's arms and legs to measure accelerations in the anterior-posterior, medial-lateral and inferior-superior directions. Subjects accomplished an extended Timed Up & Go Test (TUG). Using the eigenvectors we confirmed the hypothesis that patients with PD have asymmetrical movements of the limbs. Omitting medication 24 hours before the measurement in patients with early stage Parkinson's disease did not affect the synkinesias of walking patients. Findings suggest the possibility of the designed application of eigenvectors for use in drug therapy in patients with PD by evaluating postural stability via measuring accelerations. Thus, method using eigenvectors is newly proposed for patients with PD.

Název v anglickém jazyce

Evaluation of movement of patients with Parkinson's disease using accelerometers and method based on eigenvectors

Popis výsledku anglicky

The article focuses on a technique of quantifying movement of patients with Parkinson's disease (PD) using accelerometers and method based on eigenvectors. The method uses trend symmetry to compare acceleration's waveforms of left and right side of body. The trend symmetry value is calculated as a ratio of the variabilities of two eigenvectors, which are calculated from the kinematic motion data of left and right limb. The method utilizes eigenvectors of matrices of accelerations to compare time-normalized right leg and left leg gait cycles of patients and healthy subjects. Four accelerometers were placed on patient's arms and legs to measure accelerations in the anterior-posterior, medial-lateral and inferior-superior directions. Subjects accomplished an extended Timed Up & Go Test (TUG). Using the eigenvectors we confirmed the hypothesis that patients with PD have asymmetrical movements of the limbs. Omitting medication 24 hours before the measurement in patients with early stage Parkinson's disease did not affect the synkinesias of walking patients. Findings suggest the possibility of the designed application of eigenvectors for use in drug therapy in patients with PD by evaluating postural stability via measuring accelerations. Thus, method using eigenvectors is newly proposed for patients with PD.

Druh

D - Stať ve sborníku

CEP obor

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OECD FORD obor

20601 - Medical engineering

Projekt

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Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2016

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název statě ve sborníku

Proceedings of the 2016 17th International Conference on Mechatronics - Mechatronika (ME) 2016

ISBN

978-80-01-05883-1

ISSN

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e-ISSN

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Počet stran výsledku

5

Strana od-do

61-65

Název nakladatele

Czech Technical University in Prague, Faculty of Electrical Engineering

Místo vydání

Prague

Místo konání akce

Praha

Datum konání akce

7. 12. 2016

Typ akce podle státní příslušnosti

WRD - Celosvětová akce

Kód UT WoS článku

000400174000010