Comparison of end-expiratory lung volume measurement by electrical impedance tomography and nitrogen washout method in pigs

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21460%2F20%3A00352408" target="_blank" >RIV/68407700:21460/20:00352408 - isvavai.cz</a>

Výsledek na webu

<a href="https://doi.org/10.14311/CTJ.2020.4.05" target="_blank" >https://doi.org/10.14311/CTJ.2020.4.05</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.14311/CTJ.2020.4.05" target="_blank" >10.14311/CTJ.2020.4.05</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Comparison of end-expiratory lung volume measurement by electrical impedance tomography and nitrogen washout method in pigs

Popis výsledku v původním jazyce

End-expiratory lung volume (EELV) can be determined using several methods. Electrical impedance tomography (EIT) is offered as another method for measuring EELV. The aim of the study is to compare changes in EELV measured by nitrogen washout method with changes of EELV calculated from the change in end-expiratory lung impedance (EELI) measured by EIT and to determine whether changes in EELV calculated from changes in chest impedance can be used as one of the parameters for EIT data analysis and description. The prospective interventional animal study was performed on ten pigs. 16-electrode EIT system was used for data acquisition. The study protocol consisted of the baseline phase, two incremental PEEP steps, two decremental PEEP steps and from normal saline i. v. administration. For each breath cycle, tidal variation image was calculated as a difference between the end-inspiratory and the previous end-expiratory EIT image. An equivalent end-expiratory volume change (ΔEELVequiv) was calculated from EELI. The values of ΔEELVequiv were compared with reference EELV data measured by a modified nitrogen wash-in/wash-out technique (ΔEELVmeas). The measured and the estimated changes in EELV were statistically compared and correlation between ΔEELVequiv and ΔEELVmeas was calculated. Statistically significant difference between ΔEELVequiv and ΔEELVmeas was observed only in administration of normal saline bolus. Pearson’s correlation coefficients were 0.29 for increase in PEEP, 0.45 for decrease in PEEP and -0.1 during administration of normal saline bolus. The study showed that during changes in PEEP in the porcine model, there was no linear relationship between ΔEELVequiv and ΔEELVmeas. Although there was no linear relationship between ΔEELVequiv and ΔEELVmeas with changes in PEEP, no statistically significant difference was demonstrated between these two methods, which justifies the use of ΔEELVequiv as a parameter suitable for description and evaluation of EIT data.

Název v anglickém jazyce

Comparison of end-expiratory lung volume measurement by electrical impedance tomography and nitrogen washout method in pigs

Popis výsledku anglicky

End-expiratory lung volume (EELV) can be determined using several methods. Electrical impedance tomography (EIT) is offered as another method for measuring EELV. The aim of the study is to compare changes in EELV measured by nitrogen washout method with changes of EELV calculated from the change in end-expiratory lung impedance (EELI) measured by EIT and to determine whether changes in EELV calculated from changes in chest impedance can be used as one of the parameters for EIT data analysis and description. The prospective interventional animal study was performed on ten pigs. 16-electrode EIT system was used for data acquisition. The study protocol consisted of the baseline phase, two incremental PEEP steps, two decremental PEEP steps and from normal saline i. v. administration. For each breath cycle, tidal variation image was calculated as a difference between the end-inspiratory and the previous end-expiratory EIT image. An equivalent end-expiratory volume change (ΔEELVequiv) was calculated from EELI. The values of ΔEELVequiv were compared with reference EELV data measured by a modified nitrogen wash-in/wash-out technique (ΔEELVmeas). The measured and the estimated changes in EELV were statistically compared and correlation between ΔEELVequiv and ΔEELVmeas was calculated. Statistically significant difference between ΔEELVequiv and ΔEELVmeas was observed only in administration of normal saline bolus. Pearson’s correlation coefficients were 0.29 for increase in PEEP, 0.45 for decrease in PEEP and -0.1 during administration of normal saline bolus. The study showed that during changes in PEEP in the porcine model, there was no linear relationship between ΔEELVequiv and ΔEELVmeas. Although there was no linear relationship between ΔEELVequiv and ΔEELVmeas with changes in PEEP, no statistically significant difference was demonstrated between these two methods, which justifies the use of ΔEELVequiv as a parameter suitable for description and evaluation of EIT data.

Druh

J_SC - Článek v periodiku v databázi SCOPUS

CEP obor

—

OECD FORD obor

20601 - Medical engineering

Projekt

—

Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2020

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Lékař a technika

ISSN

0301-5491

e-ISSN

—

Svazek periodika

50

Číslo periodika v rámci svazku

4

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

6

Strana od-do

146-151

Kód UT WoS článku

—

EID výsledku v databázi Scopus

2-s2.0-85117243516