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Effect Of Prostaglandins and Beta Blockers on Progression Of Hypertensive and Normotensive Glaucomas

Identifikátory výsledku

  • Kód výsledku v IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21460%2F21%3A00347857" target="_blank" >RIV/68407700:21460/21:00347857 - isvavai.cz</a>

  • Nalezeny alternativní kódy

    RIV/61989592:15110/21:73605706

  • Výsledek na webu

    <a href="https://doi.org/10.5507/bp.2020.011" target="_blank" >https://doi.org/10.5507/bp.2020.011</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.5507/bp.2020.011" target="_blank" >10.5507/bp.2020.011</a>

Alternativní jazyky

  • Jazyk výsledku

    angličtina

  • Název v původním jazyce

    Effect Of Prostaglandins and Beta Blockers on Progression Of Hypertensive and Normotensive Glaucomas

  • Popis výsledku v původním jazyce

    The HTG group included 12 patients (mean age 66 years) with approximately the same changes in the visual field and central corneal thickness (CCT-568 um) treated with prostaglandins, and 12 patients (mean age 60 years, CCT=544 um) treated with beta-blockers. The IOP ranged from 12 to 18 mmHg for the whole follow-up period. The NTG group consisted of three subgroups. The first subgroup consisted of 14 patients (mean age 58 years) who were treated with prostaglandins. The second subgroup consisted of 10 patients (mean age 57 years) who were treated with beta blockers. The third subgroup consisted of 18 patients (mean age 57 years) who underwent no ophthalmological therapy. IOP was within the range of 8-12 mmHg over the whole follow-up period. In all patients, we monitored the pattern defect (PD) and overall defect (OD) within a period of five years. The treatment was not modified during the treatment period. All patients were compensated for cardiovascular status and had no other internal or neurological disease. Visual acuity was 1.0 with a possible correction (less than 3 dioptres) in all patients.There was no statistically significant difference in HTG during the treatment with prostaglandins in PD (P=0.35) and OD (P=0.09) or beta blockers (P=0.37 and 0.23, respectively). In NTG, the greatest changes occurred in PD (P=0.0001) in untreated patients. OD showed no statistically significant changes (P=0.25). Similarly, the patients on prostaglandins had a statistically significant difference in PD (P=0.04), while OD did not show statistically significant changes (P=0.4). We did not find statistically significant differences in progression in patients with NTG treated with beta blockers PD (P=0.7), OD (P=0.4).

  • Název v anglickém jazyce

    Effect Of Prostaglandins and Beta Blockers on Progression Of Hypertensive and Normotensive Glaucomas

  • Popis výsledku anglicky

    The HTG group included 12 patients (mean age 66 years) with approximately the same changes in the visual field and central corneal thickness (CCT-568 um) treated with prostaglandins, and 12 patients (mean age 60 years, CCT=544 um) treated with beta-blockers. The IOP ranged from 12 to 18 mmHg for the whole follow-up period. The NTG group consisted of three subgroups. The first subgroup consisted of 14 patients (mean age 58 years) who were treated with prostaglandins. The second subgroup consisted of 10 patients (mean age 57 years) who were treated with beta blockers. The third subgroup consisted of 18 patients (mean age 57 years) who underwent no ophthalmological therapy. IOP was within the range of 8-12 mmHg over the whole follow-up period. In all patients, we monitored the pattern defect (PD) and overall defect (OD) within a period of five years. The treatment was not modified during the treatment period. All patients were compensated for cardiovascular status and had no other internal or neurological disease. Visual acuity was 1.0 with a possible correction (less than 3 dioptres) in all patients.There was no statistically significant difference in HTG during the treatment with prostaglandins in PD (P=0.35) and OD (P=0.09) or beta blockers (P=0.37 and 0.23, respectively). In NTG, the greatest changes occurred in PD (P=0.0001) in untreated patients. OD showed no statistically significant changes (P=0.25). Similarly, the patients on prostaglandins had a statistically significant difference in PD (P=0.04), while OD did not show statistically significant changes (P=0.4). We did not find statistically significant differences in progression in patients with NTG treated with beta blockers PD (P=0.7), OD (P=0.4).

Klasifikace

  • Druh

    J<sub>imp</sub> - Článek v periodiku v databázi Web of Science

  • CEP obor

  • OECD FORD obor

    30207 - Ophthalmology

Návaznosti výsledku

  • Projekt

  • Návaznosti

    V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Ostatní

  • Rok uplatnění

    2021

  • Kód důvěrnosti údajů

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Údaje specifické pro druh výsledku

  • Název periodika

    Biomedical Papers

  • ISSN

    1213-8118

  • e-ISSN

    1804-7521

  • Svazek periodika

    164

  • Číslo periodika v rámci svazku

    March

  • Stát vydavatele periodika

    CZ - Česká republika

  • Počet stran výsledku

    3

  • Strana od-do

    189-191

  • Kód UT WoS článku

    000660244900013

  • EID výsledku v databázi Scopus

    2-s2.0-85100877186