Effect Of Prostaglandins and Beta Blockers on Progression Of Hypertensive and Normotensive Glaucomas
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21460%2F21%3A00347857" target="_blank" >RIV/68407700:21460/21:00347857 - isvavai.cz</a>
Nalezeny alternativní kódy
RIV/61989592:15110/21:73605706
Výsledek na webu
<a href="https://doi.org/10.5507/bp.2020.011" target="_blank" >https://doi.org/10.5507/bp.2020.011</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.5507/bp.2020.011" target="_blank" >10.5507/bp.2020.011</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Effect Of Prostaglandins and Beta Blockers on Progression Of Hypertensive and Normotensive Glaucomas
Popis výsledku v původním jazyce
The HTG group included 12 patients (mean age 66 years) with approximately the same changes in the visual field and central corneal thickness (CCT-568 um) treated with prostaglandins, and 12 patients (mean age 60 years, CCT=544 um) treated with beta-blockers. The IOP ranged from 12 to 18 mmHg for the whole follow-up period. The NTG group consisted of three subgroups. The first subgroup consisted of 14 patients (mean age 58 years) who were treated with prostaglandins. The second subgroup consisted of 10 patients (mean age 57 years) who were treated with beta blockers. The third subgroup consisted of 18 patients (mean age 57 years) who underwent no ophthalmological therapy. IOP was within the range of 8-12 mmHg over the whole follow-up period. In all patients, we monitored the pattern defect (PD) and overall defect (OD) within a period of five years. The treatment was not modified during the treatment period. All patients were compensated for cardiovascular status and had no other internal or neurological disease. Visual acuity was 1.0 with a possible correction (less than 3 dioptres) in all patients.There was no statistically significant difference in HTG during the treatment with prostaglandins in PD (P=0.35) and OD (P=0.09) or beta blockers (P=0.37 and 0.23, respectively). In NTG, the greatest changes occurred in PD (P=0.0001) in untreated patients. OD showed no statistically significant changes (P=0.25). Similarly, the patients on prostaglandins had a statistically significant difference in PD (P=0.04), while OD did not show statistically significant changes (P=0.4). We did not find statistically significant differences in progression in patients with NTG treated with beta blockers PD (P=0.7), OD (P=0.4).
Název v anglickém jazyce
Effect Of Prostaglandins and Beta Blockers on Progression Of Hypertensive and Normotensive Glaucomas
Popis výsledku anglicky
The HTG group included 12 patients (mean age 66 years) with approximately the same changes in the visual field and central corneal thickness (CCT-568 um) treated with prostaglandins, and 12 patients (mean age 60 years, CCT=544 um) treated with beta-blockers. The IOP ranged from 12 to 18 mmHg for the whole follow-up period. The NTG group consisted of three subgroups. The first subgroup consisted of 14 patients (mean age 58 years) who were treated with prostaglandins. The second subgroup consisted of 10 patients (mean age 57 years) who were treated with beta blockers. The third subgroup consisted of 18 patients (mean age 57 years) who underwent no ophthalmological therapy. IOP was within the range of 8-12 mmHg over the whole follow-up period. In all patients, we monitored the pattern defect (PD) and overall defect (OD) within a period of five years. The treatment was not modified during the treatment period. All patients were compensated for cardiovascular status and had no other internal or neurological disease. Visual acuity was 1.0 with a possible correction (less than 3 dioptres) in all patients.There was no statistically significant difference in HTG during the treatment with prostaglandins in PD (P=0.35) and OD (P=0.09) or beta blockers (P=0.37 and 0.23, respectively). In NTG, the greatest changes occurred in PD (P=0.0001) in untreated patients. OD showed no statistically significant changes (P=0.25). Similarly, the patients on prostaglandins had a statistically significant difference in PD (P=0.04), while OD did not show statistically significant changes (P=0.4). We did not find statistically significant differences in progression in patients with NTG treated with beta blockers PD (P=0.7), OD (P=0.4).
Klasifikace
Druh
J<sub>imp</sub> - Článek v periodiku v databázi Web of Science
CEP obor
—
OECD FORD obor
30207 - Ophthalmology
Návaznosti výsledku
Projekt
—
Návaznosti
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju
Ostatní
Rok uplatnění
2021
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
Biomedical Papers
ISSN
1213-8118
e-ISSN
1804-7521
Svazek periodika
164
Číslo periodika v rámci svazku
March
Stát vydavatele periodika
CZ - Česká republika
Počet stran výsledku
3
Strana od-do
189-191
Kód UT WoS článku
000660244900013
EID výsledku v databázi Scopus
2-s2.0-85100877186