X-ray photoabsorption-induced processes within protonated rifamycin sodium salts in the gas phase

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21460%2F21%3A00356434" target="_blank" >RIV/68407700:21460/21:00356434 - isvavai.cz</a>

Výsledek na webu

<a href="https://doi.org/10.1140/epjd/s10053-021-00092-w" target="_blank" >https://doi.org/10.1140/epjd/s10053-021-00092-w</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1140/epjd/s10053-021-00092-w" target="_blank" >10.1140/epjd/s10053-021-00092-w</a>

Jazyk výsledku

angličtina

Název v původním jazyce

X-ray photoabsorption-induced processes within protonated rifamycin sodium salts in the gas phase

Popis výsledku v původním jazyce

Up to now, the response of antibiotics upon ionizing radiation has been very scarcely reported. Here, we present the results of X-ray photoabsorption experiments on isolated rifamycin, a broad-range antibiotic against Gram-positive and Gram-negative bacteria. A mass spectrometer has been coupled to a synchrotron beamline to analyze cationic products of photoabsorption on protonated rifamycin dimer and monomer sodium salts. Absorption of a single photon in the 100-300eV energy range leads to ionization of the molecular system, followed by vibrational energy deposition and subsequent inter- and/or intramolecular fragmentation. Interestingly, we observe a proton transfer from sodiated rifamycin to rifamycin, a widely observed process in ionized molecular systems in the gas phase. Moreover, we show that another charge-transfer process occurs in both dimer and monomer: intramolecular sodium transfer, which has not been reported yet, to the best of our knowledge.

Název v anglickém jazyce

X-ray photoabsorption-induced processes within protonated rifamycin sodium salts in the gas phase

Popis výsledku anglicky

Up to now, the response of antibiotics upon ionizing radiation has been very scarcely reported. Here, we present the results of X-ray photoabsorption experiments on isolated rifamycin, a broad-range antibiotic against Gram-positive and Gram-negative bacteria. A mass spectrometer has been coupled to a synchrotron beamline to analyze cationic products of photoabsorption on protonated rifamycin dimer and monomer sodium salts. Absorption of a single photon in the 100-300eV energy range leads to ionization of the molecular system, followed by vibrational energy deposition and subsequent inter- and/or intramolecular fragmentation. Interestingly, we observe a proton transfer from sodiated rifamycin to rifamycin, a widely observed process in ionized molecular systems in the gas phase. Moreover, we show that another charge-transfer process occurs in both dimer and monomer: intramolecular sodium transfer, which has not been reported yet, to the best of our knowledge.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10301 - Atomic, molecular and chemical physics (physics of atoms and molecules including collision, interaction with radiation, magnetic resonances, Mössbauer effect)

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2021

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

The European Physical Journal D

ISSN

1434-6060

e-ISSN

1434-6079

Svazek periodika

75

Číslo periodika v rámci svazku

3

Stát vydavatele periodika

FR - Francouzská republika

Počet stran výsledku

9

Strana od-do

—

Kód UT WoS článku

000626034600005

EID výsledku v databázi Scopus

2-s2.0-85102059195