Development of a versatile deep hyperthermia treatment planning tool

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21460%2F25%3A00384221" target="_blank" >RIV/68407700:21460/25:00384221 - isvavai.cz</a>

Výsledek na webu

<a href="https://doi.org/10.1016/j.ejmp.2025.105035" target="_blank" >https://doi.org/10.1016/j.ejmp.2025.105035</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.ejmp.2025.105035" target="_blank" >10.1016/j.ejmp.2025.105035</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Development of a versatile deep hyperthermia treatment planning tool

Popis výsledku v původním jazyce

Purpose: To develop and test a versatile deep hyperthermia treatment planning (HTP) tool. Methods: A patient automatic positioning routine following manual clinical procedure was implemented into a newly developed versatile HTP tool. For 70 patients treated using Sigma 60 applicator, 48 patients with the Sigma Eye applicator, we compared predicted specific absorption rate (SAR) indicators obtained by manual and automatic positioning routines. We used the target to hotspot coefficient (THQ) representing the ratio between average SAR in target and hotspot, TC25 and TC50 defined as target volume enclosed with 25% and 50% SAR iso-contour. Further, we created example HTP setups for Sigma Ellipse, Alba4D and AMC8 applicators demonstrating the versatility of the tool. Results: For the Sigma 60 and the Sigma Eye, we found a highest average relative difference of 2% for all studied SAR indicators when comparing manual and automatically created HTP setups. Overall, the automatic positioning procedure is highly efficient and operator time for building a single patient specific HTP setup is 10-20 min faster. Conclusion: On average, the automatic positioning routine is more time efficient and provides similar SAR target coverage compared to manual positioning by experienced staff. The reduced time requirement supports wider HTP acceptance in the clinical routine.

Název v anglickém jazyce

Development of a versatile deep hyperthermia treatment planning tool

Popis výsledku anglicky

Purpose: To develop and test a versatile deep hyperthermia treatment planning (HTP) tool. Methods: A patient automatic positioning routine following manual clinical procedure was implemented into a newly developed versatile HTP tool. For 70 patients treated using Sigma 60 applicator, 48 patients with the Sigma Eye applicator, we compared predicted specific absorption rate (SAR) indicators obtained by manual and automatic positioning routines. We used the target to hotspot coefficient (THQ) representing the ratio between average SAR in target and hotspot, TC25 and TC50 defined as target volume enclosed with 25% and 50% SAR iso-contour. Further, we created example HTP setups for Sigma Ellipse, Alba4D and AMC8 applicators demonstrating the versatility of the tool. Results: For the Sigma 60 and the Sigma Eye, we found a highest average relative difference of 2% for all studied SAR indicators when comparing manual and automatically created HTP setups. Overall, the automatic positioning procedure is highly efficient and operator time for building a single patient specific HTP setup is 10-20 min faster. Conclusion: On average, the automatic positioning routine is more time efficient and provides similar SAR target coverage compared to manual positioning by experienced staff. The reduced time requirement supports wider HTP acceptance in the clinical routine.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

20601 - Medical engineering

Projekt

—

Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2025

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

PHYSICA MEDICA-EUROPEAN JOURNAL OF MEDICAL PHYSICS

ISSN

1120-1797

e-ISSN

1724-191X

Svazek periodika

136

Číslo periodika v rámci svazku

105035

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

9

Strana od-do

—

Kód UT WoS článku

001523209500001

EID výsledku v databázi Scopus

2-s2.0-105009003332