EVALUATION OF SIMPLIFIED MECHANICAL POWER AND DISSIPATED ENERGY CALCULATIONS IN PHYSICAL RESPIRATORY MODELS WITH TISSUE AND AIRWAY RESISTANCE

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21460%2F25%3A00386708" target="_blank" >RIV/68407700:21460/25:00386708 - isvavai.cz</a>

Výsledek na webu

<a href="https://doi.org/10.14311/CTJ.2025.1.03" target="_blank" >https://doi.org/10.14311/CTJ.2025.1.03</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.14311/CTJ.2025.1.03" target="_blank" >10.14311/CTJ.2025.1.03</a>

Jazyk výsledku

angličtina

Název v původním jazyce

EVALUATION OF SIMPLIFIED MECHANICAL POWER AND DISSIPATED ENERGY CALCULATIONS IN PHYSICAL RESPIRATORY MODELS WITH TISSUE AND AIRWAY RESISTANCE

Popis výsledku v původním jazyce

Mechanical power (MP) calculation is a promising predictor of ventilator-induced lung injury, yet simplified bedside equations rely on airway opening pressure, potentially missing key information about tissue-level stresses, and involve unclear contributions of PEEP and airway flow resistance. This study compared simplified MP equations in physical models of the respiratory system with either tissue viscoelastic (Rt) or airway flow (Raw) resistance, evaluating how pressure measurement location affects delivered and dissipated energy estimates. Six physical models (No-resistance, Tissue resistance, Flow resistance, and three combinations of Rt with different Raw) were ventilated with the same volume-controlled parameters. Pressure was measured at the airway opening and at an artificial lung level with vital signs monitor, sampled at 100 Hz. Mechanical energy was calculated using both simplified equations and a geometric method based on the pressure-volume loops. Simplified MP equations produced similar mechanical energy estimates for Tissue resistance model and Flow resistance model (Raw = 5 cmH2O.s.L-1) when pressure was measured at the airway opening. However, measurements at the artificial lung level revealed marked differences in delivered and dissipated energy. Simplified MP equations may misrepresent tissue-level energy, particularly when Raw dominates. Future studies should focus on refining energy estimation methods, considering driving transpulmonary pressures, inspiratory hold duration, and tissue versus flow resistance.

Název v anglickém jazyce

EVALUATION OF SIMPLIFIED MECHANICAL POWER AND DISSIPATED ENERGY CALCULATIONS IN PHYSICAL RESPIRATORY MODELS WITH TISSUE AND AIRWAY RESISTANCE

Popis výsledku anglicky

Mechanical power (MP) calculation is a promising predictor of ventilator-induced lung injury, yet simplified bedside equations rely on airway opening pressure, potentially missing key information about tissue-level stresses, and involve unclear contributions of PEEP and airway flow resistance. This study compared simplified MP equations in physical models of the respiratory system with either tissue viscoelastic (Rt) or airway flow (Raw) resistance, evaluating how pressure measurement location affects delivered and dissipated energy estimates. Six physical models (No-resistance, Tissue resistance, Flow resistance, and three combinations of Rt with different Raw) were ventilated with the same volume-controlled parameters. Pressure was measured at the airway opening and at an artificial lung level with vital signs monitor, sampled at 100 Hz. Mechanical energy was calculated using both simplified equations and a geometric method based on the pressure-volume loops. Simplified MP equations produced similar mechanical energy estimates for Tissue resistance model and Flow resistance model (Raw = 5 cmH2O.s.L-1) when pressure was measured at the airway opening. However, measurements at the artificial lung level revealed marked differences in delivered and dissipated energy. Simplified MP equations may misrepresent tissue-level energy, particularly when Raw dominates. Future studies should focus on refining energy estimation methods, considering driving transpulmonary pressures, inspiratory hold duration, and tissue versus flow resistance.

Druh

J_SC - Článek v periodiku v databázi SCOPUS

CEP obor

—

OECD FORD obor

20601 - Medical engineering

Projekt

—

Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2025

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Lékař a technika – Clinician and Technology

ISSN

0301-5491

e-ISSN

2336-5552

Svazek periodika

55

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

9

Strana od-do

16-24

Kód UT WoS článku

—

EID výsledku v databázi Scopus

2-s2.0-105023712102