Polypyrrole-derived low molecular weight substances induce neurogenesis in emryonic stem cells

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F70883521%3A28110%2F22%3A63560381" target="_blank" >RIV/70883521:28110/22:63560381 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/70883521:28610/22:63560381

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Polypyrrole-derived low molecular weight substances induce neurogenesis in emryonic stem cells

Popis výsledku v původním jazyce

Conductive polymers (CP) are used as biomaterials in tissue engineering due to their conductivity, biocompatibility, relatively easy of synthesis and their low cost. An advantageous aspect of CP is the combination of electronic and ionic conductivity. The ability to convert electrical signals to ionic (and vice versa) plays a crucial role in creating an active biointerface. The effect of CP conductivity is interesting in connection with the stimulation of electrosensitive tissues such as nervous or cardiac. Polypyrrole (PPy) is one of the most discussed representatives of CP in tissue engineering. There are many studies where PPy in combination with electric current affects the behavior of cells. However, the PPy precursor, heterocycle pyrrole, also has very interesting properties, as the pyrrole molecule is present in many therapeutic agents. Pyrrole derivatives serve as phannacologically active substances and clearly influencing cellular behavior.

Název v anglickém jazyce

Polypyrrole-derived low molecular weight substances induce neurogenesis in emryonic stem cells

Popis výsledku anglicky

Conductive polymers (CP) are used as biomaterials in tissue engineering due to their conductivity, biocompatibility, relatively easy of synthesis and their low cost. An advantageous aspect of CP is the combination of electronic and ionic conductivity. The ability to convert electrical signals to ionic (and vice versa) plays a crucial role in creating an active biointerface. The effect of CP conductivity is interesting in connection with the stimulation of electrosensitive tissues such as nervous or cardiac. Polypyrrole (PPy) is one of the most discussed representatives of CP in tissue engineering. There are many studies where PPy in combination with electric current affects the behavior of cells. However, the PPy precursor, heterocycle pyrrole, also has very interesting properties, as the pyrrole molecule is present in many therapeutic agents. Pyrrole derivatives serve as phannacologically active substances and clearly influencing cellular behavior.

Druh

O - Ostatní výsledky

CEP obor

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OECD FORD obor

20903 - Bioproducts (products that are manufactured using biological material as feedstock) biomaterials, bioplastics, biofuels, bioderived bulk and fine chemicals, bio-derived novel materials

Projekt

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Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2022

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů