Vitamin D supplementation in inflammatory bowel disease: the role of dosage and patient compliance

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F70883521%3A28120%2F16%3A43874462" target="_blank" >RIV/70883521:28120/16:43874462 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.4149/BLL_2016_028" target="_blank" >http://dx.doi.org/10.4149/BLL_2016_028</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.4149/BLL_2016_028" target="_blank" >10.4149/BLL_2016_028</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Vitamin D supplementation in inflammatory bowel disease: the role of dosage and patient compliance

Popis výsledku v původním jazyce

OBJECTIVES: Vitamin D substitution is recommended in patients with inflammatory bowel disease. Specific guidelines are lacking. The aim of this study was to assess the effect of vitamin D supplementation with respect to dosage and patient compliance. METHODS: A prospective cohort study of 167 Crohn disease/ulcerative colitis outpatients. Patients were screened for serum vitamin D (250HD(2+3)) at the end of summer and in late winter. Demographic data, history of vitamin D supplementation were recorded and matched with prescription records. RESULTS: A total of 57 subjects used vitamin D supplementation (mean dose 1104 IU/day). 250HD(2+3) levels were lower (p < 0.001) in winter both in substituted and unsubstituted group, without any differences between groups within the same season. 250HD(2+3) levels did not correlate with the substitution dose. 52.1 % of subjects were fully compliant with substitution. 250HD(2+3) and prevalence of vitamin D deficit in this group were comparable with unsubstituted subjects except a higher prevalence of vitamin D insufficiency (p < 0.02). CONCLUSION: Fixed dosage of 1100 IU/day of vitamin D was insufficient to correct the deficiency. Patient compliance with vitamin D supplementation was low, however this fact did not significantly contribute to the degree of vitamin D deficiency in this dosage (Tab. 3, Fig. 1, Ref. 21). Text in PDF www.elis.sk.

Název v anglickém jazyce

Vitamin D supplementation in inflammatory bowel disease: the role of dosage and patient compliance

Popis výsledku anglicky

OBJECTIVES: Vitamin D substitution is recommended in patients with inflammatory bowel disease. Specific guidelines are lacking. The aim of this study was to assess the effect of vitamin D supplementation with respect to dosage and patient compliance. METHODS: A prospective cohort study of 167 Crohn disease/ulcerative colitis outpatients. Patients were screened for serum vitamin D (250HD(2+3)) at the end of summer and in late winter. Demographic data, history of vitamin D supplementation were recorded and matched with prescription records. RESULTS: A total of 57 subjects used vitamin D supplementation (mean dose 1104 IU/day). 250HD(2+3) levels were lower (p < 0.001) in winter both in substituted and unsubstituted group, without any differences between groups within the same season. 250HD(2+3) levels did not correlate with the substitution dose. 52.1 % of subjects were fully compliant with substitution. 250HD(2+3) and prevalence of vitamin D deficit in this group were comparable with unsubstituted subjects except a higher prevalence of vitamin D insufficiency (p < 0.02). CONCLUSION: Fixed dosage of 1100 IU/day of vitamin D was insufficient to correct the deficiency. Patient compliance with vitamin D supplementation was low, however this fact did not significantly contribute to the degree of vitamin D deficiency in this dosage (Tab. 3, Fig. 1, Ref. 21). Text in PDF www.elis.sk.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

AE - Řízení, správa a administrativa

OECD FORD obor

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Projekt

—

Návaznosti

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Rok uplatnění

2016

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Bratislava Medical Journal-Bratislavske Lekarske Listy

ISSN

0006-9248

e-ISSN

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Svazek periodika

117

Číslo periodika v rámci svazku

3

Stát vydavatele periodika

SK - Slovenská republika

Počet stran výsledku

4

Strana od-do

148-151

Kód UT WoS článku

000371851500005

EID výsledku v databázi Scopus

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