3D printed scaffolds based on graphene oxide partcles and poly(styrene-butadiene-strene) thermoplastic elastomer

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F70883521%3A28610%2F22%3A63560418" target="_blank" >RIV/70883521:28610/22:63560418 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

3D printed scaffolds based on graphene oxide partcles and poly(styrene-butadiene-strene) thermoplastic elastomer

Popis výsledku v původním jazyce

The main task of this work is to fabricate and analyze the new type of scaffold based on thermoplasticelastomer (SBS - styrene-butadiene-styrene block copolymer) as a matrix and plus electricallyconductive particles (modified graphene oxide) as a filler. This combination is a suitable base for 3Dprinting, easy manipulation and finally, for cultivation of neural cells on it. Typically, scaffold can bemade in the form of a complex structure and it would show improved physical properties in terms ofmechanical stability and electrical conductivity. The fabricated masterbatches suitable for 3Dprinting will be characterized as listed below and will provide suitable mechanical properties,expectedly self-healing ability and will be in the same time electrically conducting, which isimportant from the neural tissue engineering [1].The composites are examined using differential scanning calorimetry (DSC), dynamicmechanical analysis (DMA), rotation rheometry in oscillatory mode. All mentioned tests areperformed to obtain knowledge about material behavior and adapt the parameters of the 3D printingprocess suitably. The last crucial test will be measurement of scaffold cytotoxicity, where it isexpected that fabricated materials based on graphene oxide and SBS matrix will be evaluated as noncytotoxic.

Název v anglickém jazyce

3D printed scaffolds based on graphene oxide partcles and poly(styrene-butadiene-strene) thermoplastic elastomer

Popis výsledku anglicky

The main task of this work is to fabricate and analyze the new type of scaffold based on thermoplasticelastomer (SBS - styrene-butadiene-styrene block copolymer) as a matrix and plus electricallyconductive particles (modified graphene oxide) as a filler. This combination is a suitable base for 3Dprinting, easy manipulation and finally, for cultivation of neural cells on it. Typically, scaffold can bemade in the form of a complex structure and it would show improved physical properties in terms ofmechanical stability and electrical conductivity. The fabricated masterbatches suitable for 3Dprinting will be characterized as listed below and will provide suitable mechanical properties,expectedly self-healing ability and will be in the same time electrically conducting, which isimportant from the neural tissue engineering [1].The composites are examined using differential scanning calorimetry (DSC), dynamicmechanical analysis (DMA), rotation rheometry in oscillatory mode. All mentioned tests areperformed to obtain knowledge about material behavior and adapt the parameters of the 3D printingprocess suitably. The last crucial test will be measurement of scaffold cytotoxicity, where it isexpected that fabricated materials based on graphene oxide and SBS matrix will be evaluated as noncytotoxic.

Druh

O - Ostatní výsledky

CEP obor

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OECD FORD obor

20505 - Composites (including laminates, reinforced plastics, cermets, combined natural and synthetic fibre fabrics; filled composites)

Projekt

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Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2022

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů