Composite Injectable Hydrogels for Bone Regeneration: The Synergistic Effect of Polypyrrole and BMP-2

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F70883521%3A28610%2F25%3A63594458" target="_blank" >RIV/70883521:28610/25:63594458 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Composite Injectable Hydrogels for Bone Regeneration: The Synergistic Effect of Polypyrrole and BMP-2

Popis výsledku v původním jazyce

Bone defects, especially critical-size defects, present a significant challenge in orthopedic medicine, resulting in agrowing interest in advanced biomaterials that can promote bone regeneration and possess anti-inflammatory properties.Shear-thinning hydrogels are particularly promising biomaterials for this purpose, as they can mimic the naturalextracellular matrix, support cell proliferation and differentiation, be injected into irregular defect sites, and adapt to thedefect shape. In this study, we developed a chitosan/polypyrrole composite hydrogel with BMP-2-loaded microspheresfor the treatment of critical-size bone defects.

Název v anglickém jazyce

Composite Injectable Hydrogels for Bone Regeneration: The Synergistic Effect of Polypyrrole and BMP-2

Popis výsledku anglicky

Bone defects, especially critical-size defects, present a significant challenge in orthopedic medicine, resulting in agrowing interest in advanced biomaterials that can promote bone regeneration and possess anti-inflammatory properties.Shear-thinning hydrogels are particularly promising biomaterials for this purpose, as they can mimic the naturalextracellular matrix, support cell proliferation and differentiation, be injected into irregular defect sites, and adapt to thedefect shape. In this study, we developed a chitosan/polypyrrole composite hydrogel with BMP-2-loaded microspheresfor the treatment of critical-size bone defects.

Druh

O - Ostatní výsledky

CEP obor

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OECD FORD obor

20901 - Industrial biotechnology

Projekt

<a href="/cs/project/GA24-11534S" target="_blank" >GA24-11534S: Vodivé (bio)polymerní kompozity s kovalentně vázaným polypyrrolem pro biomedicínské aplikace</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2025

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů