Mechanisms of neuronal processing of interaural disparities in the lateral superior olive

Kód výsledku v IS VaVaI

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Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Mechanisms of neuronal processing of interaural disparities in the lateral superior olive

Popis výsledku v původním jazyce

Azimuthal localization of a sound source relies on two main binaural clues: the difference in sound levels at the ears (interaural level difference, ILD) and the different times of arrival of the sound at the ears (interaural time difference, ITD). The detection and coding of the ILD and ITD are performed by the cells in the superior olivary complex, namely in the lateral and medial superior olive. It is assumed that the lateral superior olive (LSO) is responsible mainly for processing of the ILD, however, several studies suggest that in some cases it is sensitive also to the ITD. In the current work, we explore two neuronal mechanisms which are biologically plausible for the LSO operation: subtraction of firing rates and detection of coincidence of concurrent spikes. Using an analytical computational model, we analyze the theoretical performance of the two mechanisms with respect to ILD and ITD detection and we determine the precision of the processing in dependence on various paramet

Název v anglickém jazyce

Mechanisms of neuronal processing of interaural disparities in the lateral superior olive

Popis výsledku anglicky

Azimuthal localization of a sound source relies on two main binaural clues: the difference in sound levels at the ears (interaural level difference, ILD) and the different times of arrival of the sound at the ears (interaural time difference, ITD). The detection and coding of the ILD and ITD are performed by the cells in the superior olivary complex, namely in the lateral and medial superior olive. It is assumed that the lateral superior olive (LSO) is responsible mainly for processing of the ILD, however, several studies suggest that in some cases it is sensitive also to the ITD. In the current work, we explore two neuronal mechanisms which are biologically plausible for the LSO operation: subtraction of firing rates and detection of coincidence of concurrent spikes. Using an analytical computational model, we analyze the theoretical performance of the two mechanisms with respect to ILD and ITD detection and we determine the precision of the processing in dependence on various paramet

Druh

D - Stať ve sborníku

CEP obor

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OECD FORD obor

30210 - Clinical neurology

Projekt

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Návaznosti

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Rok uplatnění

2013

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název statě ve sborníku

FENS Featured Regional Meeting 2013

ISBN

978-80-260-4881-7

ISSN

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e-ISSN

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Počet stran výsledku

1

Strana od-do

318-318

Název nakladatele

Institute of Experimental Medicine AS CR, v.v.i.

Místo vydání

Praha

Místo konání akce

Praha

Datum konání akce

1. 1. 2013

Typ akce podle státní příslušnosti

CST - Celostátní akce

Kód UT WoS článku

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