Variability in concentrations of volatile metabolites emitted by genotypically different strains of Pseudomonas aeruginosa

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F75010330%3A_____%2F12%3A00009802" target="_blank" >RIV/75010330:_____/12:00009802 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1111/j.1365-2672.2012.05370.x" target="_blank" >http://dx.doi.org/10.1111/j.1365-2672.2012.05370.x</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1111/j.1365-2672.2012.05370.x" target="_blank" >10.1111/j.1365-2672.2012.05370.x</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Variability in concentrations of volatile metabolites emitted by genotypically different strains of Pseudomonas aeruginosa

Popis výsledku v původním jazyce

Aims: To charactinosa in order to evaluate their potential for use as biomarkers of lung infection in noninvasive breath analysis. Methods and Results: Volatile organic compounds (VOCs) emitted from 36 clinical strains of Ps. aeruginosa (belonging to different multilocus sequence types) cultured in liquid and on solid media were analysed by gas chromatography mass spectrometry (GC-MS) and selected ion flow tube mass spectrometry (SIFT-MS). Several previously identified VOCs were detected, including ethanol, acetone, 2-butanone, 2-pentanone, isoprene, aminoacetophenone, dimethyl sulphide, dimethyl disulphide, dimethyl trisulphide and methyl thiocyanate. Additionally, significant production of 3-methyl-butanone, acetophenone, methylthioacetate and methylthiobutanoate was observed for the first time in this study. SIFT-MS quantifications of VOCs showed high variability between genotypically distinct strains. Conclusions: The data obtained indicate that the production rates of the volatil

Název v anglickém jazyce

Variability in concentrations of volatile metabolites emitted by genotypically different strains of Pseudomonas aeruginosa

Popis výsledku anglicky

Aims: To charactinosa in order to evaluate their potential for use as biomarkers of lung infection in noninvasive breath analysis. Methods and Results: Volatile organic compounds (VOCs) emitted from 36 clinical strains of Ps. aeruginosa (belonging to different multilocus sequence types) cultured in liquid and on solid media were analysed by gas chromatography mass spectrometry (GC-MS) and selected ion flow tube mass spectrometry (SIFT-MS). Several previously identified VOCs were detected, including ethanol, acetone, 2-butanone, 2-pentanone, isoprene, aminoacetophenone, dimethyl sulphide, dimethyl disulphide, dimethyl trisulphide and methyl thiocyanate. Additionally, significant production of 3-methyl-butanone, acetophenone, methylthioacetate and methylthiobutanoate was observed for the first time in this study. SIFT-MS quantifications of VOCs showed high variability between genotypically distinct strains. Conclusions: The data obtained indicate that the production rates of the volatil

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

EE - Mikrobiologie, virologie

OECD FORD obor

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Projekt

<a href="/cs/project/GA203%2F09%2F0256" target="_blank" >GA203/09/0256: Výzkum těkavých látek uvolňovaných bakteriálními kulturami metodou hmotnostní spektrometrie v proudové trubici s vybranými ionty</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2012

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of applied microbiology

ISSN

1364-5072

e-ISSN

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Svazek periodika

113

Číslo periodika v rámci svazku

3

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

13

Strana od-do

701-713

Kód UT WoS článku

000307558800025

EID výsledku v databázi Scopus

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