First steps toward harmonized human biomonitoring in Europe: demonstration project to perform human biomonitoring on a European scale

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F75010330%3A_____%2F15%3A00010781" target="_blank" >RIV/75010330:_____/15:00010781 - isvavai.cz</a>

Výsledek na webu

<a href="http://ehp.niehs.nih.gov/wp-content/uploads/123/3/ehp.1408616.alt.pdf" target="_blank" >http://ehp.niehs.nih.gov/wp-content/uploads/123/3/ehp.1408616.alt.pdf</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1289/ehp.1408616" target="_blank" >10.1289/ehp.1408616</a>

Jazyk výsledku

angličtina

Název v původním jazyce

First steps toward harmonized human biomonitoring in Europe: demonstration project to perform human biomonitoring on a European scale

Popis výsledku v původním jazyce

For Europe as a whole, data on internal exposure to environmental chemicals do not yet exist. Characterization of the internal individual chemical environment is expected to enhance understanding of the environmental threats to health. We developed and applied a harmonized protocol to collect comparable human biomonitoring data all over Europe. In 17 European countries, we measured mercury in hair and cotinine, phthalate metabolites, and cadmium in urine of 1,844 children (5-11 years of age) and their mothers. Specimens were collected over a 5-month period in 2011-2012. We obtained information on personal characteristics, environment, and lifestyle. We used the resulting database to compare concentrations of exposure biomarkers within Europe, to identify determinants of exposure, and to compare exposure biomarkers with health-based guidelines. Biomarker concentrations showed a wide variability in the European population. However, levels in children and mothers were highly correlated. M

Název v anglickém jazyce

First steps toward harmonized human biomonitoring in Europe: demonstration project to perform human biomonitoring on a European scale

Popis výsledku anglicky

For Europe as a whole, data on internal exposure to environmental chemicals do not yet exist. Characterization of the internal individual chemical environment is expected to enhance understanding of the environmental threats to health. We developed and applied a harmonized protocol to collect comparable human biomonitoring data all over Europe. In 17 European countries, we measured mercury in hair and cotinine, phthalate metabolites, and cadmium in urine of 1,844 children (5-11 years of age) and their mothers. Specimens were collected over a 5-month period in 2011-2012. We obtained information on personal characteristics, environment, and lifestyle. We used the resulting database to compare concentrations of exposure biomarkers within Europe, to identify determinants of exposure, and to compare exposure biomarkers with health-based guidelines. Biomarker concentrations showed a wide variability in the European population. However, levels in children and mothers were highly correlated. M

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

DN - Vliv životního prostředí na zdraví

OECD FORD obor

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Projekt

<a href="/cs/project/7EX11063" target="_blank" >7EX11063: Demonstration of a study to coordinate and perform human biomonitoring on a European scale</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2015

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Environmental Health Perspectives

ISSN

0091-6765

e-ISSN

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Svazek periodika

123

Číslo periodika v rámci svazku

3

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

9

Strana od-do

255-263

Kód UT WoS článku

000352167900016

EID výsledku v databázi Scopus

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