Urinary cadmium and cotinine levels and hair mercury levels in Czech children and their mothers within the framework of the COPHES/DEMOCOPHES projects

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F75010330%3A_____%2F17%3A00011800" target="_blank" >RIV/75010330:_____/17:00011800 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11120/17:43913276

Výsledek na webu

<a href="https://link.springer.com/article/10.1007%2Fs00244-017-0412-y" target="_blank" >https://link.springer.com/article/10.1007%2Fs00244-017-0412-y</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s00244-017-0412-y" target="_blank" >10.1007/s00244-017-0412-y</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Urinary cadmium and cotinine levels and hair mercury levels in Czech children and their mothers within the framework of the COPHES/DEMOCOPHES projects

Popis výsledku v původním jazyce

The COPHES/DEMOCOPHES twin project was performed in 2011-2012 in 17 European countries to harmonize all steps of the human biomonitoring survey. Urinary cadmium, cotinine, phthalate metabolites, and hair mercury were measured in children (N = 120, 6-11 years) and their mothers of reproductive age, living in urban or rural areas. Cadmium in mothers' and children's urine was detected at a geometric mean (GM) concentration 0.227 and 0.109 mu g/L, respectively. 95th percentile (P95) was 0.655 and 0.280 mu g/L in mothers and children, respectively. No age-related, education-related, or urban versus rural differences were observed within the frame of each population group. Cadmium urinary level in mothers was about twofold compared with children. Higher levels were obtained in all smoking mothers but not in occasionally smoking or mothers and children exposed to environmental tobacco smoke (ETS). Mercury values in mothers were significantly higher in urban than in rural populations but not in children. GM and P95 for mercury in children's hair were 0.098 and 0.439 mu g/g and in mothers' hair were 0.155 and 0.570 mu g/g. Concentrations for mercury in the Czech samples were lower than European average. Hair mercury increased significantly with consumption of fish or seafood and with number of amalgam tooth fillings (in children). A positive association was found with family educational level. No influence of age was observed. Urinary cadmium and hair mercury levels were lower than health-based guidelines with one exception. High levels of urinary cotinine were found in the 12 smoking mothers (GM approximately 500 mu g/L); lower levels in occasionally smoking mothers, N = 11 (34.5 mu g/L). The mean cotinine levels in nonsmoking mothers who reported daily exposure to ETS was 10.7 mu g/L. A similar mean value (10.8 mu g/L) was obtained in six children who had daily exposure to ETS. In children without exposure to ETS, the mean cotinine level was 1.39 mu g/L urine. Cotinine in the urine of children demonstrates limited protection of the Czech children against exposure to ETS.

Název v anglickém jazyce

Urinary cadmium and cotinine levels and hair mercury levels in Czech children and their mothers within the framework of the COPHES/DEMOCOPHES projects

Popis výsledku anglicky

The COPHES/DEMOCOPHES twin project was performed in 2011-2012 in 17 European countries to harmonize all steps of the human biomonitoring survey. Urinary cadmium, cotinine, phthalate metabolites, and hair mercury were measured in children (N = 120, 6-11 years) and their mothers of reproductive age, living in urban or rural areas. Cadmium in mothers' and children's urine was detected at a geometric mean (GM) concentration 0.227 and 0.109 mu g/L, respectively. 95th percentile (P95) was 0.655 and 0.280 mu g/L in mothers and children, respectively. No age-related, education-related, or urban versus rural differences were observed within the frame of each population group. Cadmium urinary level in mothers was about twofold compared with children. Higher levels were obtained in all smoking mothers but not in occasionally smoking or mothers and children exposed to environmental tobacco smoke (ETS). Mercury values in mothers were significantly higher in urban than in rural populations but not in children. GM and P95 for mercury in children's hair were 0.098 and 0.439 mu g/g and in mothers' hair were 0.155 and 0.570 mu g/g. Concentrations for mercury in the Czech samples were lower than European average. Hair mercury increased significantly with consumption of fish or seafood and with number of amalgam tooth fillings (in children). A positive association was found with family educational level. No influence of age was observed. Urinary cadmium and hair mercury levels were lower than health-based guidelines with one exception. High levels of urinary cotinine were found in the 12 smoking mothers (GM approximately 500 mu g/L); lower levels in occasionally smoking mothers, N = 11 (34.5 mu g/L). The mean cotinine levels in nonsmoking mothers who reported daily exposure to ETS was 10.7 mu g/L. A similar mean value (10.8 mu g/L) was obtained in six children who had daily exposure to ETS. In children without exposure to ETS, the mean cotinine level was 1.39 mu g/L urine. Cotinine in the urine of children demonstrates limited protection of the Czech children against exposure to ETS.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30304 - Public and environmental health

Projekt

<a href="/cs/project/7EX11063" target="_blank" >7EX11063: Demonstration of a study to coordinate and perform human biomonitoring on a European scale</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2017

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Archives of Environmental Contamination and Toxicology

ISSN

0090-4341

e-ISSN

1432-0703

Svazek periodika

73

Číslo periodika v rámci svazku

3

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

10

Strana od-do

421-430

Kód UT WoS článku

000410258100007

EID výsledku v databázi Scopus

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