Determinants of fatal outcome in patients admitted to intensive care units with influenza, European Union 2009-2017

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F75010330%3A_____%2F19%3A00012908" target="_blank" >RIV/75010330:_____/19:00012908 - isvavai.cz</a>

Výsledek na webu

<a href="https://academic.oup.com/ofid/article/6/11/ofz462/5608594" target="_blank" >https://academic.oup.com/ofid/article/6/11/ofz462/5608594</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1093/ofid/ofz462" target="_blank" >10.1093/ofid/ofz462</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Determinants of fatal outcome in patients admitted to intensive care units with influenza, European Union 2009-2017

Popis výsledku v původním jazyce

Background. Morbidity, severity, and mortality associated with annual influenza epidemics are of public health concern. We analyzed surveillance data on hospitalized laboratory-confirmed influenza cases admitted to intensive care units to identify common determinants for fatal outcome and inform and target public health prevention strategies, including risk communication. Methods. We performed a descriptive analysis and used Poisson regression models with robust variance to estimate the association of age, sex, virus (sub)type, and underlying medical condition with fatal outcome using European Union data from 2009 to 2017. Results. Of 13 368 cases included in the basic dataset, 2806 (21%) were fatal. Age =40 years and infection with influenza A virus were associated with fatal outcome. Of 5886 cases with known underlying medical conditions and virus A subtype included in a more detailed analysis, 1349 (23%) were fatal. Influenza virus A(H1N1)pdm09 or A(H3N2) infection, age =60 years, cancer, human immunodeficiency virus infection and/or other immune deficiency, and heart, kidney, and liver disease were associated with fatal outcome; the risk of death was lower for patients with chronic lung disease and for pregnant women.

Název v anglickém jazyce

Determinants of fatal outcome in patients admitted to intensive care units with influenza, European Union 2009-2017

Popis výsledku anglicky

Background. Morbidity, severity, and mortality associated with annual influenza epidemics are of public health concern. We analyzed surveillance data on hospitalized laboratory-confirmed influenza cases admitted to intensive care units to identify common determinants for fatal outcome and inform and target public health prevention strategies, including risk communication. Methods. We performed a descriptive analysis and used Poisson regression models with robust variance to estimate the association of age, sex, virus (sub)type, and underlying medical condition with fatal outcome using European Union data from 2009 to 2017. Results. Of 13 368 cases included in the basic dataset, 2806 (21%) were fatal. Age =40 years and infection with influenza A virus were associated with fatal outcome. Of 5886 cases with known underlying medical conditions and virus A subtype included in a more detailed analysis, 1349 (23%) were fatal. Influenza virus A(H1N1)pdm09 or A(H3N2) infection, age =60 years, cancer, human immunodeficiency virus infection and/or other immune deficiency, and heart, kidney, and liver disease were associated with fatal outcome; the risk of death was lower for patients with chronic lung disease and for pregnant women.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

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OECD FORD obor

30303 - Infectious Diseases

Projekt

—

Návaznosti

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Rok uplatnění

2019

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Open Forum Infectious Diseases

ISSN

2328-8957

e-ISSN

—

Svazek periodika

6

Číslo periodika v rámci svazku

11

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

8

Strana od-do

ofz462

Kód UT WoS článku

000510169700032

EID výsledku v databázi Scopus

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