Prevalence of Borrelia burgdorferi sensu lato infection in the Czech Republic

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F75010330%3A_____%2F25%3A00015044" target="_blank" >RIV/75010330:_____/25:00015044 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/60162694:G44__/26:00564143

Výsledek na webu

<a href="https://www.sciencedirect.com/science/article/pii/S1438422124000481?pes=vor&utm_source=clarivate&getft_integrator=clarivate" target="_blank" >https://www.sciencedirect.com/science/article/pii/S1438422124000481?pes=vor&utm_source=clarivate&getft_integrator=clarivate</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.ijmm.2024.151644" target="_blank" >10.1016/j.ijmm.2024.151644</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Prevalence of Borrelia burgdorferi sensu lato infection in the Czech Republic

Popis výsledku v původním jazyce

Introduction: Lyme borreliosis (LB), an infection caused by Borrelia burgdorferi sensu lato (Bbsl), is the most common tick-borne disease in Europe. To further characterize the LB burden in the Czech Republic, we conducted a seroprevalence study and estimated the incidence of symptomatic Bbsl infections. Methods: Anti-Bbsl IgM and IgG antibodies were detected in sera collected from the adult population in 2011-2012 by enzyme-linked immunosorbent assay and immunoblot tests at the National Reference Laboratory. The incidence of symptomatic Bbsl infections was estimated from the seroprevalence results and the symptomatic proportion and duration of persistence of anti-Bbsl IgG antibodies in Bbsl-infected individuals. Surveillance under-detection of symptomatic Bbsl infections was estimated by comparing surveillance-reported and seroprevalence-based incidence. Results: Samples from 1996 adults were tested; the median age (range) was 45 (18-87) years; 1037 (52.0 %) were female. The prevalence (with 95 % confidence interval) of anti-Bbsl IgG, and IgM and/or IgG (IgM/IgG) antibodies was 6.3 % (5.3-7.5 %), and 9.5 % (8.3-10.9 %), respectively. The IgM/IgG prevalence was 7.8 % (6.5-9.2 %) in Bohemia and 15.3 % (12.2-19.0 %) in Moravia. There were an estimated 30,563 (26,550-34,962) symptomatic incident Bbsl infections in adults in the Czech Republic in 2012, for an incidence of 352.2 (306.0-402.9) symptomatic Bbsl infections per 100,000 adults per year. There were an estimated 11 (10-13) symptomatic Bbsl infections for each surveillance-reported LB case in the Czech Republic in 2012. Conclusions: There is high incidence of symptomatic Bbsl infections in the Czech Republic, particularly in Moravia. Interventions are needed to address the substantial burden of LB in the Czech Republic.

Název v anglickém jazyce

Prevalence of Borrelia burgdorferi sensu lato infection in the Czech Republic

Popis výsledku anglicky

Introduction: Lyme borreliosis (LB), an infection caused by Borrelia burgdorferi sensu lato (Bbsl), is the most common tick-borne disease in Europe. To further characterize the LB burden in the Czech Republic, we conducted a seroprevalence study and estimated the incidence of symptomatic Bbsl infections. Methods: Anti-Bbsl IgM and IgG antibodies were detected in sera collected from the adult population in 2011-2012 by enzyme-linked immunosorbent assay and immunoblot tests at the National Reference Laboratory. The incidence of symptomatic Bbsl infections was estimated from the seroprevalence results and the symptomatic proportion and duration of persistence of anti-Bbsl IgG antibodies in Bbsl-infected individuals. Surveillance under-detection of symptomatic Bbsl infections was estimated by comparing surveillance-reported and seroprevalence-based incidence. Results: Samples from 1996 adults were tested; the median age (range) was 45 (18-87) years; 1037 (52.0 %) were female. The prevalence (with 95 % confidence interval) of anti-Bbsl IgG, and IgM and/or IgG (IgM/IgG) antibodies was 6.3 % (5.3-7.5 %), and 9.5 % (8.3-10.9 %), respectively. The IgM/IgG prevalence was 7.8 % (6.5-9.2 %) in Bohemia and 15.3 % (12.2-19.0 %) in Moravia. There were an estimated 30,563 (26,550-34,962) symptomatic incident Bbsl infections in adults in the Czech Republic in 2012, for an incidence of 352.2 (306.0-402.9) symptomatic Bbsl infections per 100,000 adults per year. There were an estimated 11 (10-13) symptomatic Bbsl infections for each surveillance-reported LB case in the Czech Republic in 2012. Conclusions: There is high incidence of symptomatic Bbsl infections in the Czech Republic, particularly in Moravia. Interventions are needed to address the substantial burden of LB in the Czech Republic.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30303 - Infectious Diseases

Projekt

—

Návaznosti

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Rok uplatnění

2025

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

International Journal of Medical Microbiology

ISSN

1438-4221

e-ISSN

1618-0607

Svazek periodika

318

Číslo periodika v rámci svazku

March

Stát vydavatele periodika

DE - Spolková republika Německo

Počet stran výsledku

6

Strana od-do

151644

Kód UT WoS článku

001407740900001

EID výsledku v databázi Scopus

2-s2.0-85214012016