Paradoxes of fluoride toxicity

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F75081431%3A_____%2F20%3A00001904" target="_blank" >RIV/75081431:_____/20:00001904 - isvavai.cz</a>

Výsledek na webu

<a href="http://apps.webofknowledge.com/full_record.do?product=WOS&search_mode=GeneralSearch&qid=4&SID=C5ABlKURYcXNXgIKdtV&page=1&doc=1" target="_blank" >http://apps.webofknowledge.com/full_record.do?product=WOS&search_mode=GeneralSearch&qid=4&SID=C5ABlKURYcXNXgIKdtV&page=1&doc=1</a>

DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Paradoxes of fluoride toxicity

Popis výsledku v původním jazyce

Numerous literature sources reveal evidence that fluoride affects the activities of numerous enzymes in vitro as well as in vivo. Millions of people live in endemic fluoride areas with a severe public health problem. A plethora of data suggest that fluoride should be recognized as a developmental neurotoxicant for humans. The use of water fluoridation for the prevention of dental caries has increased the concern about adverse fluoride effects. The fluoride concentration at which a reduction in dental caries is expected is close to the level which might cause chronic pathological effects. We comment on how some of the conclusions of the recent review by Guth et al., published in Archives of Toxicology, are the emerging paradoxes in fluoride research. We show that fluoride has pluripotent effects, which might contribute to unexpected epidemics in the future.

Název v anglickém jazyce

Paradoxes of fluoride toxicity

Popis výsledku anglicky

Numerous literature sources reveal evidence that fluoride affects the activities of numerous enzymes in vitro as well as in vivo. Millions of people live in endemic fluoride areas with a severe public health problem. A plethora of data suggest that fluoride should be recognized as a developmental neurotoxicant for humans. The use of water fluoridation for the prevention of dental caries has increased the concern about adverse fluoride effects. The fluoride concentration at which a reduction in dental caries is expected is close to the level which might cause chronic pathological effects. We comment on how some of the conclusions of the recent review by Guth et al., published in Archives of Toxicology, are the emerging paradoxes in fluoride research. We show that fluoride has pluripotent effects, which might contribute to unexpected epidemics in the future.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

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OECD FORD obor

10401 - Organic chemistry

Projekt

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Návaznosti

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Rok uplatnění

2020

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Fluoride

ISSN

2253-4083

e-ISSN

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Svazek periodika

53

Číslo periodika v rámci svazku

2

Stát vydavatele periodika

NZ - Nový Zéland

Počet stran výsledku

6

Strana od-do

198-203

Kód UT WoS článku

000540771000001

EID výsledku v databázi Scopus

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