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1 231 (0,088s) •

Projekt

Structure-function relationships in MN/CA IX, a human tumor-associated cell adhesion protein (GA203/02/0405)

as a non-essential activity of carbonic anhydrase. For cell transformation, proteoglycan (PG)part of MN/CA IX seems relevant since vectors with PG insert alone remain functional. The complete MN/CA IX protein cont...

CE - Biochemie

  • 2002 - 2004
    • •
  • 3 392 tis. Kč
    • •
  • 1 668 tis. Kč
    • •
  • GA ČR
Projekt

Novel metallacarborane derivatives that exhibit inhibitory properties towards carbonic anhydrase enzyme and potential applicability in cancer therapy (GA15-05677S)

and structural biology), which is directed to specific inhibition of human carbonic anhydrases (CAs) using original metallacarborane derivatives as inhibitors of the active, in particular the CA IX enzyme. Isoforms of CAs ...

CA - Anorganická chemie

  • 2015 - 2017
    • •
  • 7 244 tis. Kč
    • •
  • 7 244 tis. Kč
    • •
  • GA ČR
Projekt

DIANA - the analytical method for the determination of enzyme inhibition (GA19-10280S)

We propose to develop an advanced high-throughput screening (HTS) pipeline for identification of potent inhibitors of medicinally relevant enzymes, such as carbonic anhydrase IX (CAIX), glutamate carboxypeptidase II (GCPII)...

Biochemical research methods

  • 2019 - 2021
    • •
  • 5 295 tis. Kč
    • •
  • 4 944 tis. Kč
    • •
  • GA ČR
Projekt

Macromolecular conjugates for targeted drug delivery, imaging and isolation of proteins based on hydrophilic polymers decorated by functional moieties (GA16-02938S)

(PSMA), carbonic anhydrase IX or viral neuraminidase), evaluate their binding...

CE - Biochemie

  • 2016 - 2019
    • •
  • 10 914 tis. Kč
    • •
  • 9 439 tis. Kč
    • •
  • GA ČR
Projekt

Study of structures of carbonic anhydrases from pathogenic Candida spp. as a tool for design of potential antimycotics (GA17-08343S)

, Candida possesses carbonic anhydrase (CA) encoded by NCE103 gene, which catalyzes...

EE - Mikrobiologie, virologie

  • 2017 - 2021
    • •
  • 7 187 tis. Kč
    • •
  • 5 444 tis. Kč
    • •
  • GA ČR
Projekt

Structure and Activity of Carbonic Anhydrase Immobilized on Amine-propyl-tethered Mesoporous Silica SBA-15 for Enhanced Capture and Sequestration of CO2 (LUAIZ24135)

as carbonate minerals at the ocean bottom. This occurs naturally at a pace too slow to remedy CO2 atmospheric excess. To expedite the first rate-limiting step of carbon dioxide capture in seawater, the use of immobilized carbon...

Physical chemistry

  • 2024 - 2027
    • •
  • 2 494 tis. Kč
    • •
  • 2 494 tis. Kč
    • •
  • MŠMT
Projekt

Reprezentation of the Czech Republic in Committee IX and XI of International Institute of Welding (LA310)

representation of CR in Committees IX and XI of professional welding society - International Institute of Welding - IIW...

JP - Průmyslové procesy a zpracování

  • 2007 - 2010
    • •
  • 470 tis. Kč
    • •
  • 405 tis. Kč
    • •
  • MŠMT
Projekt

IX th International Congress of Parasitology ICOPA IX (PG98238)

údaj již není dostupný...

EG - Zoologie

  • 1998 - 1998
    • •
  • 89 tis. Kč
    • •
  • 59 tis. Kč
    • •
  • MŠMT
Projekt

Deficiency of phosphorylase system activity in children with liver glycogenosis. (NB5993)

Glycogenosis VI, IX (phosphorylase system deficiency) causes hepatomegaly and cardiomyopathy. The determination of type is possible through enzymatic method and is necessary for genetic studies. This project enables the diagnosis of glycogen...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2000 - 2001
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  • 666 tis. Kč
    • •
  • 666 tis. Kč
    • •
  • MZ
Projekt

Molecular mechanism of cancer therapy based on photoactivation of induced endogenous protoporphyrin IX (ALA-PDT). (NC5883)

The molecular mechanism of cytotoxic effects of photodynamic therapy based on photoactivation of endogenous protoporphyrin-IX following its induction by 5 - aminolevulinic acid (ALA-PDT),will be studied. The findings will be employed to elab...

FD - Onkologie a hematologie

  • 2000 - 2002
    • •
  • 10 553 tis. Kč
    • •
  • 9 909 tis. Kč
    • •
  • MZ
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