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173 (0,079s)

Výsledek výzkumu

Generation of mRx-Cre Transgenic Mouse Line for Efficient Conditional Gene Deletion in Early Retinal Progenitors

the genetic basis of the developing retina; however, the number of retina-specific Cre lines is limited. Here we report generation of the mRx-Cre BAC transgenic mouse line of themouse Rx gene, one of the earliest determina...

EB - Genetika a molekulární biologie

  • 2013
  • Jx
  • Odkaz
Výsledek výzkumu

Stage-dependent requirement of neuroretinal Pax6 for lens and retina development

in the retina at E10.5 using an mRx-Cre transgene, after a sufficient contact between...

EB - Genetika a molekulární biologie

  • 2014
  • Jx
  • Odkaz
Výsledek výzkumu

Conditional gene deletion in the mouse lens by Cre/loxP system

Cre/loxP conditional knockout strategy has revolutionized functional genomics mice with a tissue- or time-restricted activity of Cre recombinase. The two most commonly used lens-specific Cre recombinase transgenic lines are...

Biochemistry and molecular biology

  • 2019
  • C
Výsledek výzkumu

Efficient allele conversion in mouse zygotes and primary cells based on electroporation of Cre protein

Cre-loxP recombination system is a powerful tool for genome engineering. One of its applications is found in genetic mouse models that often require to induce Cre and highly efficient protocol for Cre protein delivery into ...

Biochemistry and molecular biology

  • 2020
  • Jimp
  • Odkaz
Výsledek výzkumu

Efficient allele conversion in mouse zygotes and primary cells based on electroporation of Cre protein

Cre-loxP recombination system is a powerful tool for genome engineering. One of its applications is found in genetic mouse models that often require to induce Cre and highly efficient protocol for Cre protein delivery into ...

Biochemistry and molecular biology

  • 2021
  • Jimp
  • Odkaz
Výsledek výzkumu

Efficient allele conversion in mouse zygotes and primary cells based on electroporation of Cre protein

Cre-loxP recombination system is a powerful tool for genome engineering. One of its applications is found in genetic mouse models that often require to induce Cre and highly efficient protocol for Cre protein delivery into ...

Biochemistry and molecular biology

  • 2020
  • Jimp
  • Odkaz
Výsledek výzkumu

Generation and characterization of Aldh3-Cre transgenic mice as a tool for conditional gene deletion in postnatal cornea

Conditional gene targeting in mice by means of Cre-loxP strategy represents of the Cre recombinase. Here we describe Aldh3-Cre transgenic mice as a useful tool to the refractive power. Using a set of floxed alleles we demon...

Developmental biology

  • 2020
  • Jimp
  • Odkaz
Výsledek výzkumu

CRE promoter sites modulate alternative splicing via p300-mediated histone acetylation

) alternativeEDB exon. p300 associates with CRE sites in the promoter via the CREB containing CRE sites. Both deletion and mutation of the CRE site affected EDB alternative H4 acetylation along the FN1 gene. Consistently, p...

EB - Genetika a molekulární biologie

  • 2014
  • Jx
  • Odkaz
Výsledek výzkumu

Cosmic-Ray Extremely Distributed Observatory

-ray ensembles (CRE): groups of at least two CR with a common primary interaction and CRE scenarios, and preparing to observe unexpected physics, it is also suitable capabilities, CRE could be formed both within classical m...

Astronomy (including astrophysics,space science)

  • 2020
  • Jimp
  • Odkaz
Výsledek výzkumu

Invitation to the Cosmic Ray Extremely Distributed Observatory

Cosmic Ray Ensembles (CRE) are very large, yet not observed particle cascades). Some of CRE might have a significant spatial extent which could serve as a unique axes. An obvious, although yet not probed, CRE „detection hor...

Astronomy (including astrophysics,space science)

  • 2022
  • D
  • Odkaz
  • 1 - 10 z 173