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Výsledek výzkumu

Transcriptome analysis reveals distinct gene expression profiles in astrocytoma grades II-IV

Astrocytoma is the most prevalent form of primary brain cancer categorized into individual grades of astrocytoma by previous studies has provided some insight into dysregulation of regulatory networks associated with increasing ...

Pathology

  • 2017
  • Jimp
  • Odkaz
Výsledek výzkumu

Prognostic factors in intramedullary astrocytomas: a literature review

Astrocytomas affect a significant portion of patient with intramedullary tumors. These infiltratively growing tumors are treated by a variety of metods......

FH - Neurologie, neurochirurgie, neurovědy

  • 2009
  • Jx
Výsledek výzkumu

Molecular cytogenetic and immunochemical study of high-grade astrocytomas

We study molecular cytogenetic and immunochemical study in 15 patients with high-grade astrocytomas.

FH - Neurologie, neurochirurgie, neurovědy

  • 2003
  • D
Výsledek výzkumu

Primary and recurrent diffuse astrocytomas: genomic profile comparison reveals acquisition of biologically relevant aberrations

In this study, we present two cases of diffuse astrocytoma in which additional cytogenetic and epigenetic markers with potential influence on cell proliferation or differentiation were detected at relapse....

FD - Onkologie a hematologie

  • 2016
  • Jx
  • Odkaz
Výsledek výzkumu

Intraocular astrocytoma without phacomatosis

Astrocytic tumors occur in the retina or in the optic disc usually as a part of tuberous sclerosis complex or other phacomatosis and their isolated occurrence is rare. The authors present two adult patients in whom the diagnosis of intraocular as...

FF - ORL, oftalmologie, stomatologie

  • 2004
  • Jx
Výsledek výzkumu

Intramedullary Astrocytoma - a Series of 15 Patients and Literature Overview

Intramedullary astrocytoma is one of the less common tumors of the central nervous system. Some confusion in the literature led us to retrospectively evaluated our own series (2003-2009) and compared the results with the available literature...

FH - Neurologie, neurochirurgie, neurovědy

  • 2010
  • Jx
Výsledek výzkumu

Analysis of VEGF, Flt-1, Flk-1, nestin and MMP-9 in relation to astrocytoma pathogenesis and progression

Astrocytomas, particularly high grade astrocytoma, are brain tumors with potent angiogenic activity. Our immunohistochemical study assessed vascular endothelial growth factor (VEGF), VEGF receptors (Flk-1, and Flt-1), the intermedia...

FD - Onkologie a hematologie

  • 2009
  • Jx
Výsledek výzkumu

Comparison of MR spectroscopy and MR imaging with contrast agent in children with cerebral astrocytomas

1H-MR spectroscopy - human brain - astrocytoma - Gd-DTPA enhancement - lipids - lactate...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 1999
  • Jx
Výsledek výzkumu

Autocrine VEGF Signalling in Malignant Astrocytromas

Malignant astrocytomas are among the most angiogenic tumours. Both, pro- and anti-angiogenic mechanism control tumour neovascularization. The observation in astrocytoma progression and the key pro-angiogenic factor VEGF is often fou...

EB - Genetika a molekulární biologie

  • 2008
  • O
Výsledek výzkumu

Intramedullary astrocytoma ? a series of 15 patients and literature overview

Intramedullary astrocytoma is one of the less common tumours of the central nervous system. Certain ambiguities in the literature led us to make a retrospective review of a series of our own (2003-2009) and to compare the results with availa...

FH - Neurologie, neurochirurgie, neurovědy

  • 2010
  • Jx
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