Filtry
The role of hypoxia in expression of MDR-associated ABC transporters in (embryonic stem) cells
High level of ATP binding cassette (ABC) transporters expression is charakteristic for stem cells and various types of cancer stem cells. For multidrug resistance (MDR) are responsible ABC
ED - Fyziologie
- 2012 •
- D
Rok uplatnění
D - Stať ve sborníku
The role of hypoxia in expression of MDR-associated ABC transporters in embryonic stem cells
cancer resistance protein)(1). These transporters protect stem cells against toxic cells in vitro confirm the positive role of hypoxia in stemness maintenance (2).High level of ATP binding casset...
ED - Fyziologie
- 2012 •
- O
Rok uplatnění
O - Ostatní výsledky
The role of ATP-binding transporters associated with multi-drug resistance in stem cells
, ABCC1, and ABCG2 are common ABC-t/MDR expressed in stem cells. However, substratesATP-binding transporters (ABC-t) play various roles in regulation organism function and homeostasis from prokaryota to ma...
ED - Fyziologie
- 2013 •
- O
Rok uplatnění
O - Ostatní výsledky
The role of ABC transporters associated with multidrug resistance in stem cells
ATP-binding transporters (ABC-t) play various roles in regulation of organism function and homeostasis from prokaryote to mammals. ABC-t mediate transport mainly of lipophilic substances through cellular membranes....
ED - Fyziologie
- 2013 •
- O •
- Odkaz
Rok uplatnění
O - Ostatní výsledky
Výsledek na webu
ABC transporters in mES cells - possible role of p38 MAPK
Embryonic stem (ES) cell express relatively high amount of ABC transporters, especially ABC G2/BCRP (Apati et al. 2008). Recently was found out that ABC proteins expression could be positively reg...
EB - Genetika a molekulární biologie
- 2010 •
- O
Rok uplatnění
O - Ostatní výsledky
Detection of cancer stem cell markers in sarcomas
The identification of cancer stem cell markers represents one of the very relevant research topics because cancer stem cells play important roles in tumour is paid to the detection of CD133, ABC transp...
FD - Onkologie a hematologie
- 2012 •
- Jx •
- Odkaz
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Výsledek na webu
Thiazolidinediones Regulate the Level of ABC Transporters Expression on Lung Cancer Cells
expression of ABC transporters on lung cancer cells. Therefore, the effect of PPARgama of agonists on transcription of following ABC transporters was investigated: multidrug are substrates of ABC...
FD - Onkologie a hematologie
- 2015 •
- Jx •
- Odkaz
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Výsledek na webu
Stem Cells: Therapeutic Implications in Chemotherapy and Radiotherapy Resistance in Cancer Therapy
Cancer stem cells (CSCs) are transformed forms of normal stem cells within heterogeneous mixture of cancer cells. These are mainly responsible for the recurrence for self-renewal, DNA repair capacity, micr...
Cell biology
- 2023 •
- Jimp •
- Odkaz
Rok uplatnění
Jimp - Článek v periodiku v databázi Web of Science
Výsledek na webu
Improved accumulation of ajmalicine and tetrahydroalstonine in Catharanthus cells expressing an ABC transporter
In this thesis, the regulation of transport is investigated as a limiting factor in biosynthesis of plant secondary metabolites. CjMDR1 in Catharanthus has been selected as a model system of active transporters. CjMDR1 is a member o...
EF - Botanika
- 2009 •
- Jx
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
The stabilization of hypoxia inducible factor modulates differentiation status and inhibits the proliferation of mouse embryonic stem cells
Hypoxic conditions are suggested to affect the differentiation status of stem cells (SC), including embryonic stem cells (ESC). Hypoxia inducible factor (HIF to hypoxia. Hypoxia stabilize...
FR - Farmakologie a lékárnická chemie
- 2016 •
- Jx •
- Odkaz
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Výsledek na webu
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