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16 310 (0,097s)

Výsledek výzkumu

Plazma Free Apoptotic DNA as a Predictor of Organ Dysfunction or Death in Critically Ill Patients

The study deals with evaluation of plazma free apoptotic DNA as a predictor of organ dysfunction or death in critically ill patients......

FP - Ostatní lékařské obory

  • 2005
  • Jx
Výsledek výzkumu

Apoptotic alterations of DNA in pig tissues

Apoptotic changes were studied in pig tissues during cardiopulmonary bypass. DNA ladder assay and TUNEL test were used for detection of apoptotic DNA fragmentation. Elaborated methods were applied in human myocardi...

GJ - Choroby a škůdci zvířat, veterinární medicina

  • 1999
  • Jx
Výsledek výzkumu

Apoptotic DNA alterations in pig leukocytes after phygocytosis of bacteria are linked to maturation of the immune systém.

Apoptotic DNA alterations in pig leukocytes after phygocytosis of bacteria are linked to maturation of the immune systém.

GJ - Choroby a škůdci zvířat, veterinární medicina

  • 2003
  • Jx
Výsledek výzkumu

Prognostic significance of apoptotic and genomic plasma free DNA levels in critically ill patients

of the free apoptotic (aDNA) and genomic DNA (gDNA) in patients with failure of vital to the total plasma DNA in the critically ill was ~16fold greater than the contribution of gDNA. Apoptotic DNA levels ...

EB - Genetika a molekulární biologie

  • 2005
  • Jx
Výsledek výzkumu

Apoptotic cleavage of DNA in human lymphocyte chromatin shows high sequence specificity

Apoptotic digestion of human lymphocyte chromatin results in the appearance of large amounts of nucleosome size DNA fragments.his consensus also possesses three TA dinucleotide steps, separated by five bases (corresponding to a half...

EB - Genetika a molekulární biologie

  • 2012
  • Jx
  • Odkaz
Výsledek výzkumu

Apoptosis as an early event in the development of multiple organ failure?

We have recently developed a simple method of plasma free DNA detection, which enables us to distinguish between apoptotic and genomic (necrotic) DNA. After applying this method to the critically ill, we revealed apopto...

CE - Biochemie

  • 2005
  • Jx
Výsledek výzkumu

Apoptotic DNA fragmentation in tissues of pigs with cardiopulmonary bypass (CPB)

was carried out by usual procedure on 10 minipigs. Apoptotic cells with extensive DNA with nuclei with extensive apoptotic fragmentation was found in the dead animals. It was shown that apoptotic DNA frag...

EB - Genetika a molekulární biologie

  • 1998
  • B
Výsledek výzkumu

Effect of preoperative apheresis on the amount of apoptotic cells in peripheral blood of pigs during cardiopulmonary bypass

of apoptotic cells in blood. The presence of apoptotic cells was followed according to DNA. The experiment showed that apoptotic DNA was present in leucocytes of peripheral blood. However, the estimation ...

EB - Genetika a molekulární biologie

  • 1999
  • Jx
Výsledek výzkumu

Detection of apoptotic DNA ladder in pig leukocytes and its precision using LM - PCR (ligation mediated polymerase chain reaction).

findings by DNA ladder assay but also as an effective assay in case of non-typical apoptotic DNA ladder appearance. Moreover, LM - PCR detected an apoptotic ladder even in populations with less than 1% of apop...

EB - Genetika a molekulární biologie

  • 2002
  • Jx
Výsledek výzkumu

Apoptotic changes in pig leukocytes after phagocytosis of living bacteria

The effect of extracellular bacteria (Salmonella typhimurium) on pig leukocytes was examined in this study. DNA ladder assay was used for DNA analysis, Anexin-V-Alexa 568 and TUNEL AP for quantification of apoptotic changes...

GJ - Choroby a škůdci zvířat, veterinární medicina

  • 1999
  • D
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