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Projekt

Trk1 potassium importers - key transport systems for yeast cell fitness and multiple-stress tolerance (GA20-04420S)

plasma-membrane potential and intracellular pH. The Trk transporters of some non-conventional yeasts should have a very high transport capacity and affinity to ensure eukaryotes which is supposed to be able to qui...

Microbiology

  • 2020 - 2023
    • •
  • 4 993 tis. Kč
    • •
  • 4 993 tis. Kč
    • •
  • GA ČR
Projekt

The use of affinity chromatography for identification of sterol-binding proteins from plants (IAA4055204)

and which affinity. Data will serve for optimization of steroid structures to prepare high-affinity binding matrices for plant PBPs, their isolation and study. questions about the mode of steroid-binding and transport<...

CC - Organická chemie

  • 2002 - 2006
    • •
  • 4 941 tis. Kč
    • •
  • 2 661 tis. Kč
    • •
  • AV ČR
Projekt

Molecular mechanism of interaction between the H4-H5 loop of Na+/K+-ATPase and the binding site for cardiac glycosides (IAA7011801)

. These binding sites, however, apparently cooperate. As revealed recently, the high (E1) and low (E2) affinity ATP binding sites coexist at the functional Na+/K+ complex. There is not clear, yet, whether one binding site has differ...

BO - Biofyzika

  • 1998 - 2000
    • •
  • 1 852 tis. Kč
    • •
  • 1 075 tis. Kč
    • •
  • AV ČR
Projekt

Effect of glutamate in vitro on the high-affinity choline uptake and lipid peroxidation in brain tissue. (IZ1805)

9F - 9

  • 1994 - 1995
    • •
  • 110 tis. Kč
    • •
  • 220 tis. Kč
    • •
  • MZ
Projekt

Affinity capillary electrophoresis and electrochromatography, their use for study of biomolecular interactions (GA203/06/1044)

The methodology of high-performance electroseparation techniques, affinity capillary electrophoresis in a free-solution and open-tubular affinity capillary of these biomolecules with both low- and high-molecular ma...

CB - Analytická chemie, separace

  • 2006 - 2008
    • •
  • 2 850 tis. Kč
    • •
  • 2 850 tis. Kč
    • •
  • GA ČR
Projekt

Affinity capillary electromigration methods for selective nanoanalysis of biomolecules and investigation of their interactions (GAP206/12/0453)

A new methodology of high-performance electromigration techniques, affinity capillary electrophoresis and open-tubular affinity capillary electrochromatography characterization of their interactions. New affinity l...

CB - Analytická chemie, separace

  • 2012 - 2014
    • •
  • 9 592 tis. Kč
    • •
  • 9 592 tis. Kč
    • •
  • GA ČR
Projekt

Preparation of lectins with high specificity and affinity (GPP207/11/P185)

to bind carbohydrates with very high affinity and specificity, are called lectins patients. One of the lectin displays an affinity for fucose in micromolar range, unusually high for monosaccharides binding. Search...

BO - Biofyzika

  • 2011 - 2014
    • •
  • 1 839 tis. Kč
    • •
  • 1 839 tis. Kč
    • •
  • GA ČR
Projekt

Are the High and Low Affinity ATP Binding Sites of Na,K-ATPase Different or Identical? (GA204/95/0624)

CE - Biochemie

  • 1995 - 1997
    • •
  • 750 tis. Kč
    • •
  • 750 tis. Kč
    • •
  • GA ČR
Projekt

Construction of recombinant mimotopes for induction of neutralizing antibodies against HIV-1 gp120 glycoprotein using high-affinity binders approach (NV15-32198A)

mimicking epitopes recognized by above bn-mAbs using high-affinity binders approachDevelopment of vaccine preventing HIV-1 infection is hindered by high variability of envelope glycoprotein (Env), known target for neutrali...

EC - Imunologie

  • 2015 - 2018
    • •
  • 6 200 tis. Kč
    • •
  • 6 200 tis. Kč
    • •
  • MZ
Projekt

Synthesis and supramolecular properties of bambusurils (GA13-15576S)

recently. These macrocycles act as receptors which bind various anions with high affinity and selectivity. Until now only four bambusuril derivatives was reported to prepare bambusurils with tuned properties such as enhanced solubi...

CC - Organická chemie

  • 2013 - 2017
    • •
  • 5 972 tis. Kč
    • •
  • 5 972 tis. Kč
    • •
  • GA ČR
  • 1 - 10 z 9 951