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Výsledek výzkumu

Monoclonal antibodies neutralizing circulating SARS-CoV-2 variants of concern

Variants of the SARS-CoV-2 virus emerge while it circulates within human population. They carry mutations mostly localized to the Spike protein, which drives the neutralizing activities of the host’s immune ...

Immunology

  • 2023
  • O
  • Odkaz
Výsledek výzkumu

How do anti-SARS-CoV-2 IgG and IgM predict the titre of virus-neutralizing antibodies in donors of convalescent plasma against COVID-19 disease?

, specifically to compare the correlation of serological tests of anti-SARS-CoV-2 antibodies with the virus neutralization test. for its administration is a sufficient virus neutralizing ...

Infectious Diseases

  • 2022
  • JSC
  • Odkaz
Výsledek výzkumu

Human neutralizing antibodies to cold linear epitopes and subdomain 1 of the SARS-CoV-2 spike glycoprotein

of proteolytic cleavage. Antibody hr2.016 targets the stem helix and neutralizes SARS-CoV-2 antibodies that are crossreactive with Orthocoronavirinae, including SARS-CoV-2

Virology

  • 2023
  • Jimp
  • Odkaz
Výsledek výzkumu

Successful Early Use of Anti-SARS-CoV-2 Monoclonal Neutralizing Antibodies in SARS-CoV-2 Infected Hematological Patients - A Czech Multicenter Experience

administration of anti-SARS-CoV-2 spike protein neutralizing monoclonal antibodies (NmAbs of 575 SARS-CoV-2 positive hematological patients untreated with any ...

Hematology

  • 2022
  • Jimp
  • Odkaz
Výsledek výzkumu

Five Commercial Immunoassays for SARS-CoV-2 Antibody Determination and Their Comparison and Correlation with the Virus Neutralization Test

a virus neutralization test and comparing the results of SARS-CoV-2 antibodiesThere is an ongoing debate as to whether SARS-CoV-2 antibodies can be found conclude that ...

Infectious Diseases

  • 2021
  • Jimp
  • Odkaz
Výsledek výzkumu

Multicentric evaluation of sensitivity of eight commercial anti-SARS-CoV-2 antibody assays and their correlation to virus neutralization titers in seropositive subjects

IgG NovaTec (r = 0.7103) and Anti-SARS-CoV-2 ELISA IgG Euroimmun (r = 0.7094Diagnosis of SARS-CoV-2 virus is mainly based on direct detection-CoV-2 antibody le...

Virology

  • 2024
  • Jimp
  • Odkaz
Výsledek výzkumu

Bispecific IgG neutralizes SARS-CoV-2 variants and prevents escape in mice

neutralizes wild-type SARS-CoV-2 and its variants of concern, as well as escape mutantsNeutralizing antibodies that target the receptor-binding domain (RBD) of the SARS-CoV-...

Zoology

  • 2021
  • Jimp
  • Odkaz
Výsledek výzkumu

Bispecific IgG neutralizes SARS-CoV-2 variants and prevents escape in mice

neutralizes wild-type SARS-CoV-2 and its variants of concern, as well as escape mutantsNeutralizing antibodies that target the receptor-binding domain (RBD) of the SARS-CoV-...

Medical laboratory technology (including laboratory samples analysis; diagnostic technologies) (Biomaterials to be 2.9 [physical characteristics of living material as related to medical implants, devices, sensors])

  • 2021
  • Jimp
  • Odkaz
Výsledek výzkumu

Monoclonal antibodies targeting two immunodominant epitopes on the Spike protein neutralize emerging SARS-CoV-2 variants of concern

the new variants of SARS-CoV-2. Findings AX290 and AX677, two monoclonal antibodiesBackground The emergence of new SARS-CoV-2 variants of concern B.1.1.7 (Alpha SARS-

Virology

  • 2022
  • Jimp
  • Odkaz
Výsledek výzkumu

Content and specificity of the Anti-SARS-CoV-2 antibodies in solutions for immunoglobulin replacement therapy.

: IRT solutions contain high concentrations of anti-SARS-CoV-2 specific antibodies-infection immune responses against severe acute respiratory syndrome coronavirus-2 (SARS-CoV-

Immunology

  • 2023
  • Jimp
  • Odkaz
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