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297 (0,076s) •

Projekt

The influence of hypothermia on the incidence and severity of vasospasm in patients after a severe subarachnoid hemorrhage (NA7671)

Vascular vazospasms after the subarachnoid hemorrhage is a feared complication with a high morbiditry and mortality. Neuroprotective effect of mild controlled hypothermia should decrease the incidence and severity of vazospasms and ...

FH - Neurologie, neurochirurgie, neurovědy

  • 2003 - 2005
    • •
  • 2 283 tis. Kč
    • •
  • 2 283 tis. Kč
    • •
  • MZ
Projekt

Correlation of parameters of multimodal monitoring in secondary brain trauma and its treatment in patients with brain injury and subarachnoid hemorrhage (NT13883)

Patients with traumatic brain injury (TBI) and subarachnoid hemorrhage (SAH) in the acute phase are in the risk of brain ischemia Multimodal monitoring (MMM) may provide early diagnosis of brain ischemia and thus extend the therapeu...

FH - Neurologie, neurochirurgie, neurovědy

  • 2012 - 2015
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  • 5 256 tis. Kč
    • •
  • 3 592 tis. Kč
    • •
  • MZ
Projekt

Monitoring of tissue oxymetry and cerebral blood flow for detection and treatment of cerebral ischemia in patients after severe subarachnoid hemorrhage (NT11092)

Ischemic complications after severe subarachnoid hemmorhage cause high mortality of these patients. Modern monitoring methods (tissue oxymetry, tissue blood flow) should enable timely detection of ischemia onset and also serve as the indicat...

FH - Neurologie, neurochirurgie, neurovědy

  • 2010 - 2013
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  • 5 068 tis. Kč
    • •
  • 5 068 tis. Kč
    • •
  • MZ
Projekt

Regulation of inflammatory response by microRNAs in experimental model of subarachnoid hemorrhage (GP14-23773P)

Aneurysmal subarachnoid hemorrhage (SAH) is a serious condition associated with high mortality and that is the reason why is SAH intensively studied in both clinical and experimental conditions. Cerebral vasospasm and more recently ...

FH - Neurologie, neurochirurgie, neurovědy

  • 2014 - 2018
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  • 2 932 tis. Kč
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  • 2 932 tis. Kč
    • •
  • GA ČR
Projekt

Effect of intrathecally administered vasodilators on subarachnoid hemorrhage-induced cerebral vasospasm. Animal model experiment. (NT14426)

Vasospasm induced by nontraumatic subarachnoid bleeding is an important cause of ischaemic neurological damage among patients sustaining aneurysmal subarachnoid haemorrhage. Pathophysiology of this process is not fully understood. A...

FH - Neurologie, neurochirurgie, neurovědy

  • 2013 - 2015
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  • 4 505 tis. Kč
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  • 4 020 tis. Kč
    • •
  • MZ
Projekt

Tissue Plasminogen Activator in Patients with Aneurysmal Subarachnoid Hemorrhage. (IZ2642)

9F - 9

  • 1995 - 1995
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  • 0 tis. Kč
    • •
  • 0 tis. Kč
    • •
  • MZ
Projekt

The Role of Inflammtion on Vasospasm Development in Patients after Subarachnoid Hemorrhage (NT14590)

Inflammation plays an important role in pathophysiology of SAH. Inflammatory response is started early after the SAH and it participates in vasospasm development, which are a serious complication of this disease. We can assume that inflammatory respo...

FH - Neurologie, neurochirurgie, neurovědy

  • 2013 - 2015
    • •
  • 4 602 tis. Kč
    • •
  • 4 602 tis. Kč
    • •
  • MZ
Projekt

Kynurenines and their role in the inflammatory response and pathophysiology of cerebral vasospasms following the aneurysmal subarachnoid hemorrhage (NW25-04-00246)

Aneurysmal subarachnoid hemorrhage (aSAH) is a severe neurovascular disease requiring intensive active approach driven by multidisciplinary team in Neurointensive care unit. After aSAH, a complex cascade of neuroinflammatory process...

Neurosciences (including psychophysiology)

  • 2025 - 2028
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  • 13 891 tis. Kč
    • •
  • 13 891 tis. Kč
    • •
  • MZ
Projekt

Proteomic identification of biomarkers associated with IL-6 variability in aneurysmal subarachnoid hemorrhage (NU23-04-00382)

Inflammatory response plays a pivotal role in the pathophysiology of subarachnoid hemorrhage (SAH). The inflammatory response is triggered immediately after SAH and contributes to both early brain injury (EBI) and delayed cerebral i...

Clinical neurology

  • 2023 - 2026
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  • 9 639 tis. Kč
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  • 9 639 tis. Kč
    • •
  • MZ
Projekt

Psychological consequencies of subarachnois hemorraghe and aneurysmal treatment (NF6616)

Nonrandomised longitudinal study focused at the influence of subarachnoid hemorrhage and cerebral aneurysms treatment on the psychic outcome. Four groups of patients will be studied. l.Patients with AN SAH treated by AN clipping. 2....

FH - Neurologie, neurochirurgie, neurovědy

  • 2001 - 2003
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  • 2 238 tis. Kč
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  • 2 238 tis. Kč
    • •
  • MZ
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