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467 (0,166s)

Projekt

Polymorphism of the androgen receptor gene (SNP rs6152) relationship to expression of the androgen-sensitive genes in benign prostatic hyperplasia, carcinoma of the prostate and androgenetic (NS9940)

The below mentioned hypotheses will be tested using appropriate prospective as well as retrospective sample of patients with BPH, CaP and AGA. AR gene polymorphism (SNP rs6152) can have impact not only on incidence but also on cours...

FD - Onkologie a hematologie

  • 2008 - 2011
  • 4 883 tis. Kč
  • 4 510 tis. Kč
  • MZ
Projekt

HLA polymorphism and polymorphism of cytokine genes in pemphigus vulgaris (MEB080892)

Research aim of the project is to investigate gene polymorphism (single nucleotide polymorphisms), particularly of TH2 cytokines (IL-4, IL-5, IL-6) and proinflammatory cytokines (IL-1, TNF, IFN-γ) in Slovak patients with pemphi...

EE - Mikrobiologie, virologie

  • 2008 - 2009
  • 24 tis. Kč
  • 24 tis. Kč
  • MŠMT
Projekt

The role of genetic variations in microRNA genes and in microRNA binding sites in colorectal cancer in relation to personalized therapy (NV15-26535A)

in colorectal cancer (CRC). Single nucleotide polymorphisms (SNPs) in miRNA genes and in 3 outcome. Our recent results on the effect of SNPs in miRNA binding sites of DNA repair genes provided the rationale to expand the s...

EB - Genetika a molekulární biologie

  • 2015 - 2018
  • 6 414 tis. Kč
  • 6 414 tis. Kč
  • MZ
Projekt

Identification of inherited DNA polymorphisms in genes of testosterone synthetic pathway as factors of genetic predisposition to development of prostate cancer and their use in prevention (NR8039)

. SNP polymorphisms from genes involved in testosterone synthetic pathway (CYP17Proposed project is focused on clinical study of inherited genetic polymorphisms and their association with prostate cancer for their potential...

FD - Onkologie a hematologie

  • 2004 - 2006
  • 4 906 tis. Kč
  • 4 618 tis. Kč
  • MZ
Projekt

A new biochip platform for efficient forensic sample identification and genealogical determination (FW12010208)

nucleotide polymorphisms" (SNP). This chip will be able to analyze up to 10 thousand selected SNP markers, which will provide a robust basis for genetic tests used to introduce a financially available technology based on <...

Analytical chemistry

  • 2025 - 2027
  • 21 240 tis. Kč
  • 14 869 tis. Kč
  • TA ČR
Projekt

Effects of environmental factors, gene predisposition and psychological impact of genetic testing on efficacy of lipid lowering treatment (NS10579)

Evaluation of the impact of genetic determination of dyslipidemia on therapeutic efficacy of statin treatment by assessment of gene polymorphisms. Assessment of impact of genetic testing awareness on efficacy of statin treatment.......

FA - Kardiovaskulární nemoci včetně kardiochirurgie

  • 2009 - 2011
  • 4 883 tis. Kč
  • 4 883 tis. Kč
  • MZ
Projekt

The role of genetic variation in key molecules of Th17 immune response in individual susceptibility to prosthetic joint infection (GP310/09/P377)

). This project aims at investigating single nucleotide polymorphisms (SNP) within key molecules of Th17 immune response in PJI. The SNPs in genes coding for IL-4, 17, 35, 12B levels of selected cytokines with the most rele...

EC - Imunologie

  • 2009 - 2011
  • 996 tis. Kč
  • 996 tis. Kč
  • GA ČR
Projekt

Analysis of candidate genes influencing carcass traits in pigs by positional candidate gene approach (GA523/00/0669)

will be analyzed for polymorphism and linkage with QTLs in three three-generation Hohenheim andstructure. In chromosomal regions with large effects DNA polymorphisms due to single base substitution (SNPs) will be studied b...

GI - Šlechtění a plemenářství hospodářských zvířat

  • 2000 - 2002
  • 4 453 tis. Kč
  • 3 200 tis. Kč
  • GA ČR
Projekt

Immunity-related genes in Equids genetic diversity and comparative genomics (GA523/06/1402)

. Comparison with the Old Kladruber horses will be made. Polymorphisms in known IR genes will be typed and new genes and SNPs will be sought. Comparative approach will be used for identifying conserved genes in Equids. The genes wil...

GJ - Choroby a škůdci zvířat, veterinární medicina

  • 2006 - 2008
  • 3 764 tis. Kč
  • 3 764 tis. Kč
  • GA ČR
Projekt

Fine association mapping of the porcine chromosome 2q region influencing meat quality and study of positional candidate genes (GAP502/10/1216)

proposal is fine multimarker association mapping of this chromosome region using SNPs. In the first period about 25 evenly spaced gene-tagged SNPs will be developed. Genotyping and association analyses of these SNPs will b...

GI - Šlechtění a plemenářství hospodářských zvířat

  • 2010 - 2012
  • 3 889 tis. Kč
  • 3 889 tis. Kč
  • GA ČR
  • 1 - 10 z 467