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11 (0,067s)

Projekt

In-utero origin of childhood acute myeloid leukaemias (NE7436)

The aim of the project is to show that specific leukaemogenic aberrations affect cells already during in-utero development and that such pre-leukaemic clone is capable to cause acute myeloid leukaemia in childhood.......

EB - Genetika a molekulární biologie

  • 2003 - 2005
  • 2 079 tis. Kč
  • 2 062 tis. Kč
  • MZ
Projekt

In utero origin in childhood acute lymphblastic leukemia. (NE6292)

The aim of proposed study is to identily relationships between presence of cells with specific leukaemic markers at birth and onset of leukaemia. Clonospecific rearrangemente of TCR and Ig and /or TEL/AML1 will be used for backtracking of leukemia in...

FD - Onkologie a hematologie

  • 2000 - 2002
  • 2 121 tis. Kč
  • 2 121 tis. Kč
  • MZ
Projekt

Impact of maternal immune activation on serotonergic system in the fetoplacental unit and fetal, juvenile and adult neurodevelopment (GA22-08045S)

, thereby identifying potential avenues for addressing neurological disorders in utero....

Neurosciences (including psychophysiology)

  • 2022 - 2024
  • 10 077 tis. Kč
  • 10 041 tis. Kč
  • GA ČR
Projekt

Cannabis use in pregnancy; effects on endocrine and immune functions of the placenta (GA23-07094S)

hormones, neurotransmitters, and mediators, thus providing optimal in utero conditions...

Reproductive biology (medical aspects to be 3)

  • 2023 - 2025
  • 8 997 tis. Kč
  • 8 997 tis. Kč
  • GA ČR
Projekt

Lipidome of vernix caseosa comprehensive analysis and biological variability (GAP206/12/0750)

The project deals with lipids of vernix caseosa (VC), a biofilm that coats human fetus during the last stages of pregnancy. VC serves many functions during development in utero, delivery and first days after birth, but most of them are poorl...

CB - Analytická chemie, separace

  • 2012 - 2017
  • 3 966 tis. Kč
  • 3 966 tis. Kč
  • GA ČR
Projekt

Programming of the developing heart by maternal diabetes (GA16-06825S)

the offspring to a number of chronic diseases later in life, indicating a role for in utero...

EA - Morfologické obory a cytologie

  • 2016 - 2018
  • 8 193 tis. Kč
  • 7 914 tis. Kč
  • GA ČR
Projekt

The effect of diabetes compensation on placental function and fetal circulation in pregnant women with type 1 diabetes mellitus. (NU20-01-00067)

in utero development given by the presence of diabetes and placental dysfunction...

Endocrinology and metabolism (including diabetes, hormones)

  • 2020 - 2024
  • 12 724 tis. Kč
  • 12 675 tis. Kč
  • MZ
Projekt

Placental tryptophan metabolism linking maternal inflammation and foetal neurodevelopmental disorders (NU20-01-00264)

potential avenues for addressing neurological disorders in utero....

Endocrinology and metabolism (including diabetes, hormones)

  • 2020 - 2023
  • 9 740 tis. Kč
  • 9 665 tis. Kč
  • MZ
Projekt

Antidepressants in pregnancy; effect on placental transport and metabolism of serotonin (GA20-13017S)

, or platelets), it is feasible to assume that suboptimal 5-HT levels in utero could...

Pharmacology and pharmacy

  • 2020 - 2022
  • 7 592 tis. Kč
  • 7 592 tis. Kč
  • GA ČR
Projekt

Processing of complex acoustical signals including vocalizations in inhibitory circuits of the central auditory system in mice models of autism and different types of sensorineural hearing loss. (LTAIN19201)

PROPERTIES IN IN-UTERO VPA EXPOSURE BASED MOUSE MODEL OF ASD AND DIFFERENT HL AIM 6...

Neurosciences (including psychophysiology)

  • 2020 - 2022
  • 6 829 tis. Kč
  • 6 829 tis. Kč
  • MŠMT
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