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219 089 (0,257s)

Výsledek výzkumu

Effectiveness of first-line anticancer treatment may predict treatment response in further lines in stage III/IV patients with non-small cell lung cancer

in the first line during the years 2011-2019. ,,Succesful treatment " was defined used.ResultsThe first-line TKI therapy was successful in 66.2%, while good responders (up to 70%). Good ...

Oncology

  • 2023
  • Jimp
  • Odkaz
Výsledek výzkumu

Comparison of interim PET response to second-line vs. to first-line treatment in classical Hodgkin lymphoma - contribution to the development of response criteria for relapsed or progressive disease

Rationale: In first-line treatment of Hodgkin lymphoma (HL) Deauville scores 1 response to first-line and to second-line treatment in 127 patients with classical used to systematically an...

Hematology

  • 2021
  • Jimp
  • Odkaz
Výsledek výzkumu

Preservative-free tafluprost in the treatment of naive patients with glaucoma and ocular hypertension

In this real-world observational study, treatment with once-daily preservative-free tafluprost proved efficacious, well tolerated, and safe in treatment-naive patients....

FF - ORL, oftalmologie, stomatologie

  • 2013
  • Jx
  • Odkaz
Výsledek výzkumu

Preservative-free tafluprost in the treatment of naive patients with glaucoma and ocular hypertension

The study reported here investigated the efficacy, tolerability, and safery of the preservative-free prostaglandin analog tafluprost 0.0015% in treatment-naive patiens....

FF - ORL, oftalmologie, stomatologie

  • 2013
  • Jx
  • Odkaz
Výsledek výzkumu

Pharmacotherapy of obsessive-compulsive disorder

Serotonine reuptake inhibitors (SRIs) are the first line of drugs in treatment first and venlafaxine later. In non responders and partial responders, atypical profile. High doses and longer trials...

FL - Psychiatrie, sexuologie

  • 2009
  • Jx
  • Odkaz
Výsledek výzkumu

Basic pharmacological treatment of generalized anxiety disorder

characterized by the presence of generalized anxiety and excessive worry. Current treatment consists of a range of pharmacological and psychological treatments. However, many patients do not respond to first-l...

Psychiatry

  • 2024
  • JSC
  • Odkaz
Výsledek výzkumu

First-line treatment of metastatic renal cell carcinoma

Renal cell cancer accounts 2-3% of all cases of malignancy. Sunitinib and pazopanib have so far been standard in first-line treatment of metastatic renal cell cancer. In this review we discuss current first-lin...

Oncology

  • 2019
  • O
Výsledek výzkumu

Transmembrane glycoprotein GPNMB is a potential marker of poor response of metastatic renal cell carcinoma to tyrosine kinase receptor inhibitor treatment

(rTKI) has been used in the first-line treatment of mRCC patients with good or intermediate prognosis for many years. However, about half of the patients respond poorly or do not respond to this treat...

Biochemistry and molecular biology

  • 2023
  • O
Výsledek výzkumu

Rituximab maintenance for 2 years in patients with high tumour burden follicular lymphoma responding to rituximab plus chemotherapy (PRIMA): a phase 3, randomised controlled trial

Patients with follicular lymphoma can have long survival times, but disease progression typically occurs 3-5 years after initial treatment. We assessed the potential benefit of 2 years of rituximab maintenance after first-line

FD - Onkologie a hematologie

  • 2011
  • Jx
  • Odkaz
Výsledek výzkumu

Imatinib in the first-line treatment of chronic myelogenous leukemia in chronic phase

Imatinib in the first-line treatment of chronic myelogenous leukemia in chronic phase...

FD - Onkologie a hematologie

  • 2008
  • Jx
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