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Projekt

TTAGG telomeric repeats in chromosome of insects and other arthropods (GA206/00/0750)

Telomeres, the physical ends of chromosomes in eukaryotes, are specialized DNA-protein structures that have a number of essential function for chromosome biology in insect I, lineage but was lost independently in different ...

EB - Genetika a molekulární biologie

  • 2000 - 2002
  • 2 718 tis. Kč
  • 1 410 tis. Kč
  • GA ČR
Projekt

Composition of plant kinetochores and its evolutionary plasticity in the context of centromere organization (GA25-15809S)

kinetochore protein composition and plasticity among evolutionarily distant plant groupsThe kinetochore is a complex multiprotein structure that connects chromosomes to spindle microtubules and ensures chromosome ...

Genetics and heredity (medical genetics to be 3)

  • 2025 - 2027
  • 10 332 tis. Kč
  • 10 332 tis. Kč
  • GA ČR
Projekt

Analysis of 3D organization of nuclear genome in plants with contrasting amount of DNA (LTC18026)

proteins indicative of specific chromosome domains (e.g. centromere, telomere and organization of large chromatin domains and chromosomes in different cell cycle stages/develop mutants in several complexes known to control...

Cell biology

  • 2018 - 2021
  • 4 428 tis. Kč
  • 4 428 tis. Kč
  • MŠMT
Projekt

Evolution of the karyotype and sex chromosomes in tetrapulmonate lineage of arachnids (GA206/08/0813)

. Therefore,tetrapulmonates can be excellent group for study of sex chromosome differentiation. In selected groups, evolution of sex chromosomes will be studied in detail chromosomes in tetrapulmonate clad...

EB - Genetika a molekulární biologie

  • 2008 - 2010
  • 2 681 tis. Kč
  • 2 681 tis. Kč
  • GA ČR
Projekt

The evolution of the sex chromosome system X1X20 in spiders (GA206/98/P250)

of very numerous group of spiders has not been extensively investigated. The project deals with secondary systems of sex chromosomes which substitutes in certain spider groups typeX1X20 (Amaurobioidea, Dictynoidea). The ev...

EG - Zoologie

  • 1998 - 2001
  • 674 tis. Kč
  • 656 tis. Kč
  • GA ČR
Projekt

Mutational analysis of structure-specific DNA-binding HMG-box B motif of nonhistone chromosomal protein HMG1 (IAA5004604)

The HMG (high mobility group) domain has recently been identified as a new DNA-binding motif in a number of DNA-binding proteins and transcription factors. Chromosomal protein HMG1 contains two HMG-box domains (A a...

CE - Biochemie

  • 1996 - 1998
  • 1 865 tis. Kč
  • 1 462 tis. Kč
  • AV ČR
Projekt

Molecular analysis of the structure and function of typical and alternative telomeres in plants (GA204/02/0027)

Telomeres, nucleoprotein complexes forming the ends of eukaryotic chromosomes, namely in the field of telomere-binding proteins, specific featuresof chromatin is focused on the study of so called alternative telomeres in a wide ...

EB - Genetika a molekulární biologie

  • 2002 - 2004
  • 4 982 tis. Kč
  • 2 843 tis. Kč
  • GA ČR
Projekt

Maternal ageing effect on activities of major protein kinases regulating mammalian meiosis. (GAP502/10/0944)

Chromosomal aneuploidy is the major cause of premature abortions in humans. Most of the chromosomal abnormalities have been shown to be of maternal origin of chromosomal aneuploidy. Although predisposition to chromosoma...

EB - Genetika a molekulární biologie

  • 2010 - 2013
  • 3 628 tis. Kč
  • 3 628 tis. Kč
  • GA ČR
Projekt

Molecular evolution and functional analysis of components of plant telomeres and telomerases (GA521/05/0055)

Telomeres are nucleoprotein structures protecting chromosome ends from transcriptase (TERT) and telomerase RNA (TR), to replenish ends of chromosomal DNA lost with the evolution of novel types of telomeres. In addition to group<...

EB - Genetika a molekulární biologie

  • 2005 - 2007
  • 3 792 tis. Kč
  • 3 792 tis. Kč
  • GA ČR
Projekt

Characterization of selected candidate factors contributing to nondisjunction of the maize B chromosome (GA25-16290S)

B chromosomes, also known as supernumerary chromosomes, are genetic elements is the nondisjunction of the maize B chromosome, where individual chromatids fail to segregate factors that may be involved in the nondisjunction ...

Genetics and heredity (medical genetics to be 3)

  • 2025 - 2027
  • 9 954 tis. Kč
  • 9 954 tis. Kč
  • GA ČR
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