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Projekt

IMMUNO - INFLAMMATORY MECHANISMS IN PATHOGENESIS OF NASAL POLYPOSIS (NR8517)

Activated mucosal immune cells in nasal polyps. Role of growth factors, cytokines and chemokines in NP. Innate immune mechanisms in pathogensis of nasal polyposis. Role of non-endothelial expression of ICAMs in nasal polyposis.......

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 2005 - 2007
    • •
  • 2 279 tis. Kč
    • •
  • 2 279 tis. Kč
    • •
  • MZ
Projekt

Molecular analysis of the APC and MYH genes in families affected with familial adenomatous polyposis or multiple adenomas (NR8103)

polyposis....

FD - Onkologie a hematologie

  • 2004 - 2006
    • •
  • 2 846 tis. Kč
    • •
  • 2 810 tis. Kč
    • •
  • MZ
Projekt

The Diagnostics of Extraesophageal Reflux with the Restech System in Patients with Chronic Rhinosinusitis (NT13500)

different patient groups (1. CHR without nasal polyposis, without asthma bronchiale or ASA syndrome, 2. CHR with nasal polyposis, without asthma bronchiale or ASA syndrome, 3. CHR with nasal polyposis and asthma bronchiale...

FF - ORL, oftalmologie, stomatologie

  • 2012 - 2015
    • •
  • 2 626 tis. Kč
    • •
  • 2 469 tis. Kč
    • •
  • MZ
Projekt

Presymptomatic DNA diagnostics of familial adenomatous polyposis coli. (IZ2308)

9F - 9

  • 1994 - 1996
    • •
  • 965 tis. Kč
    • •
  • 1 360 tis. Kč
    • •
  • MZ
Projekt

The study of the syndrome of aspirin intorelance as a risk factor in patients with nasal polyps. (IZ4051)

The goal of the study is to identify by challenge test among the patients with nasal polyposis the ones with incomplete syndrome of aspirin intolerance. These patients are likely to be threatened with bronchial asthma.They will be examined b...

FF - ORL, oftalmologie, stomatologie

  • 1997 - 1999
    • •
  • 1 124 tis. Kč
    • •
  • 867 tis. Kč
    • •
  • MZ
Projekt

Molecular and cellular mechanisms in ethiopathogenesis of nasal polyposis (NS10054)

Signaling pathways and changes in expression of intracellular signaling molecules in nasal polyps. Expression of Toll-like receptors as potential markers for identifying etiological environmental factors in nasal polyps. Changes in expression of chem...

FF - ORL, oftalmologie, stomatologie

  • 2008 - 2011
    • •
  • 2 140 tis. Kč
    • •
  • 2 140 tis. Kč
    • •
  • MZ
Projekt

Clinical and pothogenetic aspects of telomerase activity in colorectal and breast cancer with respect to their sporadic versus hereditary occurence (NC6741)

value will be established. In members of hereditary non-polyposis colon cancer...

FD - Onkologie a hematologie

  • 2001 - 2003
    • •
  • 2 544 tis. Kč
    • •
  • 2 502 tis. Kč
    • •
  • MZ
Projekt

Quality and safety of food in relation to colorectal cancer predisposition. A pilot study (7F10069)

changes (adenomatous polyposis) and malignancies in the colon. Addressing differences...

EB - Genetika a molekulární biologie

  • 2010 - 2010
    • •
  • 381 tis. Kč
    • •
  • 381 tis. Kč
    • •
  • MŠMT
Projekt

The relation between the occurence of the bacteria Staphylococcus aureus on the mucosa of the nose and paranasal sinusis and mucosal antimicrobial activity expressed by the presence of defensins (NR8440)

Staphylococcus aureus is often found as part of the normal microflora of the upper respiratory tract especially the vestibulum naší.Pathogenicity of S.aureus is closely corellated with production of toxins with superantigenic properties. The pathogen...

FP - Ostatní lékařské obory

  • 2005 - 2007
    • •
  • 1 710 tis. Kč
    • •
  • 1 458 tis. Kč
    • •
  • MZ
Projekt

Nasal microbiome and molecular immune mechanisms in the prevention and pathogenesis of nasal polyps and chronic rhinitis; relation to olfactory disorders and allergies (NU22-09-00493)

Chronic rhinosinusitis (CRS) and CRS with nasal polyps (CRSwNP) represent a frequent and recurrent chronic inflammatory affection in the ENT practice. The pathogenesis of the CRS and NP is not fully understood and optimal treatment preventing high re...

Otorhinolaryngology

  • 2022 - 2025
    • •
  • 9 234 tis. Kč
    • •
  • 9 234 tis. Kč
    • •
  • MZ
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