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2 642 (0,072s) •

Projekt

Trichomonad hydrogenosomes, electrontransporting pathways and drug resistance (GA204/06/0944)

metronidazole activator, as trichomonads engineered without ferredoxin did not acquire metronidazole resistance. Other factors that lay behind the resistance encountered has negative side effects and resistant...

EB - Genetika a molekulární biologie

  • 2006 - 2008
    • •
  • 2 667 tis. Kč
    • •
  • 2 667 tis. Kč
    • •
  • GA ČR
Projekt

Characteristics of isolates of Giardia intestinalis, a causative agent of the most common intestinal protozoan infection, as diagnostic tools (NV15-33369A)

recommended doses of metronidazole is increasing mainly in travelers returning from India and test them in vitro for sensitivity to metronidazole (MTZ), the most commonly used drug for treatment of the infection, to collect isolate...

EE - Mikrobiologie, virologie

  • 2015 - 2018
    • •
  • 8 134 tis. Kč
    • •
  • 8 134 tis. Kč
    • •
  • MZ
Projekt

Molecular mechanism of metronidazole resistance in trichomonads (GA204/97/0263)

of metronidazole reistance in the sexually transmitted protozoan pathogen of humans Trichomonas. A set of drug resistant lines derived from a common drug susceptible strain and representing major phases in resistance devel...

EE - Mikrobiologie, virologie

  • 1997 - 1999
    • •
  • 2 604 tis. Kč
    • •
  • 2 069 tis. Kč
    • •
  • GA ČR
Projekt

New approaches to addressing giardiasis treatment failure the employment of next-generation sequencing and digital PCR in the search for markers of parasite drug resistance. e. (NU23-05-00441)

do not even respond to the increased dosage of metronidazole (MTZ), the drug with clinically resistant giardiasis are subsequently treated with a combination of tinidazole be eliminated by laboratory markers that would detect r...

Microbiology

  • 2023 - 2026
    • •
  • 12 893 tis. Kč
    • •
  • 12 893 tis. Kč
    • •
  • MZ
Projekt

Giardiosis in dogs in the Czech Republic - prevalence and therapy (PG99114)

asymptomatic. Because of increased resistence of metronidazoles, we tried benzimidazoles...

GJ - Choroby a škůdci zvířat, veterinární medicina

  • 1999 - 1999
    • •
  • 78 tis. Kč
    • •
  • 38 tis. Kč
    • •
  • MŠMT
Projekt

Targets for chemotherapy of infections with anaerobic Protozoa rezistant to 5-nitroimidazoles (OC B9.10)

The objective of the project is to study mechanisms of resistance of anaerobic for therapy of nitroimidazole-resistant organisms. Drug resistance studies will focus activation process and on alternative metabolic pathways e...

EE - Mikrobiologie, virologie

  • 1999 - 2002
    • •
  • 3 205 tis. Kč
    • •
  • 1 655 tis. Kč
    • •
  • MŠMT
Projekt

Iron-sulfur cluster biosynthesis in Giardia intestinalis mitosomes and their role in cellular metabolism and antibiotic resistance. (GA23-06888S)

in antibiotic resistance. Finally, we investigate the uptake and the intracellular route...

Biochemistry and molecular biology

  • 2023 - 2025
    • •
  • 9 368 tis. Kč
    • •
  • 9 368 tis. Kč
    • •
  • GA ČR
Projekt

Clostridium difficile genotyping and phenotyping of clinically significant isolates - a survey of the epidemiological situation in the Czech Republic (NT14209)

of choice - metronidazole,vancomycin and fidaxomicin will be determined. It is expected...

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 2013 - 2015
    • •
  • 3 038 tis. Kč
    • •
  • 2 860 tis. Kč
    • •
  • MZ
Projekt

Prevalence of critical types of antimicrobial resistance in etiological agents of infectious diseases in farm animals (QH91231)

to the selection of resistant microorganisms. Therefore, the antimicrobial policy should spread of antimicrobial resistance (either directly by resistant microorganisms or indirectly by genetic determinants of resistan...

GJ - Choroby a škůdci zvířat, veterinární medicina

  • 2009 - 2011
    • •
  • 5 528 tis. Kč
    • •
  • 4 821 tis. Kč
    • •
  • MZe
Projekt

Resistance monitoring methods of economically important pests and weeds to pesticides and anti-resistance strategies (QK1820081)

The aim of the project is to verify or develop methods for resistance organisms with incidence of resistance in Europe. Resistance of pests of oil seed rape, field vegetable and potatoes and weeds will be evaluated. For

Agronomy, plant breeding and plant protection; (Agricultural biotechnology to be 4.4)

  • 2018 - 2020
    • •
  • 15 680 tis. Kč
    • •
  • 15 680 tis. Kč
    • •
  • MZe
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