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Filtry

1 802 (0,064s) •

Projekt

Role of cytosine in the conformational polymorphism of DNA (IAA4004701)

cytosine-rich NA fragments: Characterization of a thermostable conformer that oligo(dC. The anomalousconformation of d(CnGn) oligonucleotides.Duplex,G-quadruplex and i-quadruplex formation in the d(CnGn) and d(GnC...

BO - Biofyzika

  • 1997 - 1999
    • •
  • 3 750 tis. Kč
    • •
  • 1 425 tis. Kč
    • •
  • AV ČR
Projekt

The role of auxin and auxin-amino acid conjugate hydrolases during male gametophyte development of Arabidopsis thaliana (GP13-41444P)

Not only oriented transport of auxin, but also the formation of auxin conjugates with aminoacids together with hydrolase activity releasing biologically active auxin from conjugated forms, is responsible for proper spatial and temporal to id...

ED - Fyziologie

  • 2013 - 2017
    • •
  • 3 750 tis. Kč
    • •
  • 3 750 tis. Kč
    • •
  • GA ČR
Projekt

Exploration of properties and preparation of metalloporfyrin derivatives of Tröger’s, spiro-Tröger’s, and oligo-Tröger’s bases (LTAUSA19065)

The goal is to elaborate methods for preparation of molecules consisting of metalloporhyrin as the joint arene part of: a) two or more Tröger’s bases–new family of chiral receptors and catalysts; b) two spiro-Tröger’s bases–new family of light harves...

Organic chemistry

  • 2019 - 2022
    • •
  • 6 681 tis. Kč
    • •
  • 6 681 tis. Kč
    • •
  • MŠMT
Projekt

Preparation of molecular containers based on oligo-Tröger's bases and study of their chemical sensing ability (GPP207/11/P121)

The project deals with preparations and studying properties of molecular containers based on oligo-Tröger's bases. This new class of compounds, discovery in applicant laboratory, feature with ability to isomerise in acidic medium, wherein so...

CB - Analytická chemie, separace

  • 2011 - 2013
    • •
  • 1 500 tis. Kč
    • •
  • 1 500 tis. Kč
    • •
  • GA ČR
Projekt

Structure and synergism of fibrolytic enzymes in the rumen (GA16-12431S)

The aim of the project is description of glycobiome and synergism of individual hydrolases of dominant G+ rumen hemicellulolytic species related to genera Butyrivibrio species and to describe unusual glycosyl hydrolases, their hydro...

EE - Mikrobiologie, virologie

  • 2016 - 2020
    • •
  • 4 284 tis. Kč
    • •
  • 4 032 tis. Kč
    • •
  • GA ČR
Projekt

Development of macromolecular x-ray crystallography and computer-aided modelling for genetic engineering and drug design in the Czech and Slovak Republics (OK 169)

BO - Biofyzika

  • 1996 - 1997
    • •
  • 613 tis. Kč
    • •
  • 208 tis. Kč
    • •
  • MŠMT
Projekt

Crystal structures and bonding in non-metal compounds of the V., VI. , and VII. group of the periodic systém (GA203/98/0676)

The project deals with crystal structures and character of bonding in compounds cosntaining elements of the V., VI., and VII. group. The research will concentrate on the following classes of compounds: (a) structure of betaines of substituted (ol...

CA - Anorganická chemie

  • 1998 - 2000
    • •
  • 1 677 tis. Kč
    • •
  • 1 327 tis. Kč
    • •
  • GA ČR
Projekt

The role of increased epoxyeicosatrienoic acids level in the regulation of renal function and pathophysiology of renovascular hypertension (NS9699)

This proposal is designed to determine whether inhibitors of soluble epoxide hydrolase (sEH), increasing endogenous level of epoxyeicosatrienoic acids (EETs), could be a potential new approach in antihypertensive drug therapy. An effects of ...

ED - Fyziologie

  • 2008 - 2011
    • •
  • 3 119 tis. Kč
    • •
  • 3 119 tis. Kč
    • •
  • MZ
Projekt

Multi-FRET fluorescent probes responding to hydrolases (GA19-23972S)

The project is focused on synthesis of model systems for detection of two or three proteases solely or in their mixture via fluorescence multi-FRET effect. The systems will be based on three/four dyes connected with linkers cleavable by the proteins....

Organic chemistry

  • 2019 - 2021
    • •
  • 5 070 tis. Kč
    • •
  • 5 070 tis. Kč
    • •
  • GA ČR
Projekt

Pharmacological blockade of both the endothelin system and soluble epoxyde hydrolase as a new aproach to the treatment of hypertensive organ damage (NV15-28671A)

availability of EETs, by soluble epoxyde hydrolase (sEH) inhibition, will decrease blood...

FA - Kardiovaskulární nemoci včetně kardiochirurgie

  • 2015 - 2019
    • •
  • 8 880 tis. Kč
    • •
  • 8 880 tis. Kč
    • •
  • MZ
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