Filtry
Advanced glycation and oxidadion end-products and their signifficance in the pathogenesis of chronic diseases and their complications (NB7035)
The aim of the project is to study markers of advanced damage - advanced glycation and oxidation end-products together with other parameters of oxidative stress and inflammation in patients with renal dise...
FP - Ostatní lékařské obory
- 2002 - 2004 •
- 2 076 tis. Kč •
- 2 076 tis. Kč •
- MZ
Řešení projektu: 1. 1. 2002 - 1. 1. 2004
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Ministerstvo zdravotnictví
Modification of enzymes metabolizing xenobiotics during ageing (GP524/09/P121)
On ageing of animal organisms, proteins are impaired by oxidation and glycation of proteins (non-enzymatic glycation and glycoxidation). Physiological functions of glycated proteins are impaired and glycated enzyme...
CE - Biochemie
- 2009 - 2011 •
- 1 143 tis. Kč •
- 1 143 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2009 - 31. 12. 2011
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Grantová agentura České republiky
Monoclonal antibodies to selected advanced glycation end products (AGE), development of ELISA, and correlation of AGE levels in sera of patients with rheumatoid arthritis and systemic lupus (NR9122)
We will prepare monoclonal antibodies to two major products of non-enzyme glycation of proteins (AGE), Ne-(carboxymethyl) lysine and pentosidine, and to other AGE, generated by reaction of proteins with glucose, and develop ELISA. B...
FP - Ostatní lékařské obory
- 2006 - 2009 •
- 4 514 tis. Kč •
- 4 057 tis. Kč •
- MZ
Řešení projektu: 1. 1. 2006 - 31. 12. 2009
Uznané náklady
Podpora ze státního rozpočtu (90%)
Poskytovatel: Ministerstvo zdravotnictví
Bone metabolism in patients with type 2 diabetes mellitus role of the receptor for advanced glycation end products (RAGE) and its gene polymorphism (NT11335)
advanced glycation end products (AGEs), its soluble receptor (sRAGE) and polymorphism...
FB - Endokrinologie, diabetologie, metabolismus, výživa
- 2010 - 2015 •
- 6 978 tis. Kč •
- 6 978 tis. Kč •
- MZ
Řešení projektu: 1. 9. 2010 - 31. 12. 2015
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Ministerstvo zdravotnictví
Modulation of the advanced glycation and lipoxidation end products using various treatments in renal transplant recipients (NR8018)
Patients in chronic renal insufficiency show increased levels of AGEs and ALEs. Our study is designed to establish the contributions made by development of graft function and the therapy to the decrease in these products seen after renal tra...
FJ - Chirurgie včetně transplantologie
- 2004 - 2006 •
- 2 429 tis. Kč •
- 2 322 tis. Kč •
- MZ
Řešení projektu: 1. 1. 2004 - 1. 1. 2006
Uznané náklady
Podpora ze státního rozpočtu (96%)
Poskytovatel: Ministerstvo zdravotnictví
Determination of Pentosidinine in Etiopathogenesis of Rheumatic and Diabetic Diseases and Influence of its Level by the Medication with Vitamin C in Glycation and Oxidation Stress of the Organism (NR7895)
HPLC determination of pentosidine (advanced glycation product)formed in arthritis and diabetes mellitus. Exploitation of pentosidine as an indicator of glycoxidation loading and influence of vitamin C on inhibition of glyco...
FP - Ostatní lékařské obory
- 2004 - 2006 •
- 1 741 tis. Kč •
- 1 727 tis. Kč •
- MZ
Řešení projektu: 1. 1. 2004 - 1. 1. 2006
Uznané náklady
Podpora ze státního rozpočtu (99%)
Poskytovatel: Ministerstvo zdravotnictví
Advanced glycation endproducts (AGE) and their receptors - effects of vitamin C on the prevention of angiopathy. (IZ1435)
9F - 9
- 1993 - 1995 •
- 333 tis. Kč •
- 666 tis. Kč •
- MZ
Řešení projektu: 1. 1. 1993 - 1. 1. 1995
Uznané náklady
Podpora ze státního rozpočtu (200%)
Poskytovatel: Ministerstvo zdravotnictví
The effect of advanced glycation end products and lipid oxidation and gene polymorphism on the progression of renal insufficiency in obese patients (NR8509)
Obesity is a major risk factor in patients with renal disease, and is associated with accelerated progression of renal insufficiency. Obesity is associated with metabolic complications (hyperlipidemia, hyperhomocysteinemia, hyperleptinemia, increased...
FE - Ostatní obory vnitřního lékařství
- 2005 - 2007 •
- 2 793 tis. Kč •
- 2 455 tis. Kč •
- MZ
Řešení projektu: 1. 1. 2005 - 31. 12. 2007
Uznané náklady
Podpora ze státního rozpočtu (88%)
Poskytovatel: Ministerstvo zdravotnictví
Effects of dietary Advanced Glycation End products in the Alzheimer?s Disease Mouse Model Tg2576 (LH13254)
The aim of this study is to evaluate the effects of a low AGE diet on the AD-like amyloidosis and cholinergic decrease that develops in the transgenic Tg2576 mice. Our primary hypothesis is that an increased dietary intake of AGE accelerates the form...
FH - Neurologie, neurochirurgie, neurovědy
- 2013 - 2015 •
- 1 336 tis. Kč •
- 1 336 tis. Kč •
- MŠMT
Řešení projektu: 15. 3. 2013 - 31. 5. 2015
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Ministerstvo školství, mládeže a tělovýchovy
New aspects of heterotopic ossification processes in diffuse idiopathic skeletal hyperostosis, ankylozing spondylitis, and ossification of the posterior longitudinal ligament (NK7732)
of the level of pentosidine which is a representative of advanced glycation endproducts...
FE - Ostatní obory vnitřního lékařství
- 2003 - 2005 •
- 2 691 tis. Kč •
- 2 671 tis. Kč •
- MZ
Řešení projektu: 1. 1. 2003 - 1. 1. 2005
Uznané náklady
Podpora ze státního rozpočtu (99%)
Poskytovatel: Ministerstvo zdravotnictví
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