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941 (0,088s)

Projekt

Improvement of the diagnostics of disorders of growth hormone secretion with the follow- up of growth hormone binding protein and IGF-binding protein 3 (IZ2344)

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 1994 - 1997
  • 589 tis. Kč
  • 706 tis. Kč
  • MZ
Projekt

Binding proteins of IGF in hypopituitary patients treated with growth hormone. (NB5458)

IGF I binding proteins, Western Blotting, fragmentation, therapy with growth hormone. The examination of IGF I binding proteins including their low and high molecular forms and proteolytic fragments will contribute...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 1999 - 2001
  • 1 914 tis. Kč
  • 1 914 tis. Kč
  • MZ
Projekt

Electrophoresis and Western Blotting of IGF I Binding Preoteins in Disorders of the Growth Hormone -IGF-I Axis. (IZ3661)

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 1996 - 1998
  • 1 489 tis. Kč
  • 1 399 tis. Kč
  • MZ
Projekt

Analogues of insulin, IGF-1 and IGF-2 to study their neuroprotective effects in neurons and glial cells. (GA22-17978S)

. Broader knowledge of possible positive influence of insulin, IGF-1 or IGF-2 therapies basal and neuroprotective effects of several unique insulin, IGF-1 and IGF-2 analogues with significantly altered receptor

Cell biology

  • 2022 - 2024
  • 9 928 tis. Kč
  • 9 017 tis. Kč
  • GA ČR
Projekt

Control of protein accretion and lipid deposition by peptide and steroid hormone analogues (IAA7045608)

Peptide analogues with sequences corresponding to the intrachinary region of insulin, IGF-I and IGF-II will be synthetized by recently developed solid state methods (Velek et al., 1994) and their abilities to affect metabolic activi...

ED - Fyziologie

  • 1996 - 1998
  • 1 951 tis. Kč
  • 722 tis. Kč
  • AV ČR
Projekt

Insulin mimetics (GA14-17305S)

of compounds mimicking three noncontiguous receptor-binding epitopes in insulin molecule. Mixtures of compounds will be tested for their binding to both isoforms of insulin receptor and to the receptor for IGF-1 and for ot...

FR - Farmakologie a lékárnická chemie

  • 2014 - 2016
  • 7 721 tis. Kč
  • 7 721 tis. Kč
  • GA ČR
Projekt

Towards molecular separation of metabolic and mitogenic effects of insulin and IGF-2 (GA15-19018S)

Insulin and IGF-2 are related hormones that control key aspects of metabolism and growth in tissues. Although insulin and IGF-2 have distinct physiological roles IR-B or IR-A and IGF-1R. Deregulation of receptors leads to t...

CE - Biochemie

  • 2015 - 2017
  • 6 705 tis. Kč
  • 6 705 tis. Kč
  • GA ČR
Projekt

Prospective study of factors influencing postnatal growth and factors that constitute risk of certain diseases in adulhood in children born small for gestational age and in children with extremely low birth weight (NR9374)

) is associated with low birth weight and low IGF-I levels. Some polymorphism of IGF-I gene correlates with IGF-I levels, decreasing levels of IGF-I according to age and patternof pre - and postnatal growth. The ai...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2007 - 2009
  • 8 692 tis. Kč
  • 8 656 tis. Kč
  • MZ
Projekt

Differential expression of Pregnancy Associated Plasma Protein - A (PAPP-A) and Insulin-like growth factor-binding protein 4 (IGFBP4) in follicular fluid and blood of women in correlation (NR8932)

Whether concentrations and composition of PAPP-A a IGFBP4 complexes in follicular fluid and blood due to ovarian hormonal stimulation for in vitro fertilisation have relations with the degree of subsequent ovarian hyperstimulation syndrome (OHSS). Th...

FK - Gynekologie a porodnictví

  • 2006 - 2008
  • 2 766 tis. Kč
  • 1 711 tis. Kč
  • MZ
Projekt

Peptides from the Intrachinary Regions of Insulin, IGF I, IGF II. Synthesis, Physiochemical and Biological Properties (GA505/93/2140)

GM - Potravinářství

  • 1993 - 1995
  • 286 tis. Kč
  • 572 tis. Kč
  • GA ČR
  • 1 - 10 z 941