Filtry
Insight into the toxic effects of cis-dichloridoplatinum(II) complexes containing 7-azaindole halogeno derivatives in tumor cells
Potential factors which might be involved in the mechanism underlying the cytotoxic effects of the cisplatin analogues cis-[PtCl2(3ClHaza)2] and cis-[PtCl2(3IHaza)2] (3ClHaza and 3IHaza are 3-chloro-7-azaindole and 3-iodo-7...
BO - Biofyzika
- 2013 •
- Jx •
- Odkaz
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Výsledek na webu
Gold(I) N-heterocyclic carbene complexes show strong proapoptotic, antioxidant and anti-inflammatory effects in A2780 and endothelial cells
)] based on 1,3-bis(2,4,6-trimethylphenyl)imidazole-2-ylidene (IMes) and 7-azaindole derivatives (HLn), where n = 1-8 for HL1 = 5-fluoro7-azaindole, HL2 = 5-bromo-7-azaindole, HL3 = 3-chloro-7-
Inorganic and nuclear chemistry
- 2025 •
- Jimp •
- Odkaz
Rok uplatnění
Jimp - Článek v periodiku v databázi Web of Science
Výsledek na webu
Utilization of the dichlorido complexes of platinum with 7-azaindole halogeno-derivatives for the preparation of drugs for the treatment of tumour diseases
The invention relates to the utilization of the platinum dichlorido complexes involving the 7-azaindole halogeno-derivatives for the preparation of drugs for the treatment of tumour diseases, concretely for the treatment of ovarian ...
CA - Anorganická chemie
- 2012 •
- P
Rok uplatnění
P - Patent
Dichlorido complexes of platinum with 7-azaindole halogeno-derivatives for use in the treatment of tumour diseases
The invention relates to the utilization of the platinum(II) dichlorido complexes involving the 7-azaindole halogeno-derivatives for the preparation of drugs for the treatment of human tumour diseases, conretely for the treatment of...
CA - Anorganická chemie
- 2015 •
- P •
- Odkaz
Rok uplatnění
P - Patent
Výsledek na webu
Dichlorido complexes of platinum with 7-azaindole halogeno-derivatives and application of these complexes as drugs in antitumor therapy
The invention, that belongs to the area of the platinum-based drugs of tumor diseases, relates to the platinum dichlorido complexes involving the 7-azaindole derivatives, their preparation using M2[PtCl4], where M is H, K, or Na ato...
CA - Anorganická chemie
- 2012 •
- Fuzit
Rok uplatnění
Fuzit - Užitný vzor
Dichlorido complexes of platinum with 7-azaindole derivatives, method of their preparation and application of these complexes as drugs in antitumor therapy
The invention, that belongs to the area of the platinum-based drugs of tumor diseases, relates to the platinum dichlorido complexes involving the 7-azaindole derivatives, their preparation using M2[PtCl4], where M is H, K, or Na ato...
CA - Anorganická chemie
- 2012 •
- P
Rok uplatnění
P - Patent
Gold(I) N-Heterocyclic Carbene Complexes with 7-Azaindoles Demonstrates In Vitro Antiproliferative Effects on Ovarian Cancer Cells and Anti-inflammatory Activity
of 1,3-bis(2,6-diisopropylphenyl)imidazole-2-ylidene (iPr) and the corresponding 7-azaindole derivative (HL1-4), were prepared and characterized. The complexes of the composition of [Au(iPr)(Ln)], where n = 1-4 for 5-fluoro-7
Inorganic and nuclear chemistry
- 2024 •
- Jimp •
- Odkaz
Rok uplatnění
Jimp - Článek v periodiku v databázi Web of Science
Výsledek na webu
Potentiation of cytotoxic action of cis-[PtCl2(NH3)(1M7AI)] by UVA irradiation. Mechanistic insights
potentiate the toxicity of a cisplatin derivative, cis-[PtCl2(NH3) (1-methyl-7-azaindole of cis[PtCl2(NH3)(1-methyl-7-azaindole)] is connected with the capability oxygen, conditioned by the presence of the 1-methy...
Biochemistry and molecular biology
- 2018 •
- Jimp •
- Odkaz
Rok uplatnění
Jimp - Článek v periodiku v databázi Web of Science
Výsledek na webu
Synthesis, Characterization and in Vitro Antitumor Activity of Platinum(II) Oxalato Complexes Involving 7-Azaindole Derivatives as Coligands
-chloro-7-azaindole (4Claza; 1), 3-bromo-7-azaindole (3Braza; 2) or 4-bromo-7-azaindole (4Braza; 3). The prepared substances were screened for their in vitro......
CA - Anorganická chemie
- 2014 •
- Jx •
- Odkaz
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Výsledek na webu
How to modify 7-azaindole to form cytotoxic Pt(II) complexes: Highly in vitro anticancer effective cisplatin derivatives involving halogeno-substituted 7-azaindole
The platinum(II) dichlorido and oxalato complexes of the general formula cis-[PtCl2(nHaza)(2)] (1-3) [Pt(ox)(nHaza)(2)] (4-6) involving 7-azaindole halogeno-derivatives (nHaza) were prepared and thoroughly characterized. A single-cr...
CA - Anorganická chemie
- 2012 •
- Jx •
- Odkaz
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Výsledek na webu
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