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2 393 (0,094s) •

Projekt

Mechanisms of spindle assembly in acentriolar eukaryotic cells (IAA5020803)

and molecular motors ensure bipolar spendle assembly in acentriolar cells. In vitro of microtubules in the vicinity of nuclear envelope or chromosomes and their assembly and biochemical manipulations to microtubule ass...

EA - Morfologické obory a cytologie

  • 1998 - 2001
    • •
  • 3 397 tis. Kč
    • •
  • 1 548 tis. Kč
    • •
  • AV ČR
Projekt

Study of the role of gamma-tubulin complexes in high plant acentrosomal cells by in vitro polymerization of tubulin (GP204/02/D068)

with major grant we will apply in vitro assays for animal and plant tubulin polymerization developed in our previous grant. Association of g-tubulin with microtubules, polarity of plantmicrotubules polymerized in vitro...

EA - Morfologické obory a cytologie

  • 2002 - 2005
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  • 3 366 tis. Kč
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  • 747 tis. Kč
    • •
  • GA ČR
Projekt

Mechanistic insights into microtubule polyglutamylations by tubulin tyrosine ligase-like 11 (TTLL-11) (GA23-07149S)

variants together with tubulins harboring defined post-translational modifications in a reconstituted in vitro system to unravel mechanisms of tubulin polyglutamylation by TTLL11 of the dominant modifications is polyglutam...

Biochemistry and molecular biology

  • 2023 - 2025
    • •
  • 9 864 tis. Kč
    • •
  • 9 864 tis. Kč
    • •
  • GA ČR
Projekt

Analysis of signaling assemblies containing gamma-tubulin (GA204/09/1777)

Gamma-tubulin is involved in the nucleation of microtubules from microtubule organizing centers. Recent data document that gamma-tubulin is also associated in regulation of gamma-tubulin functions in mast cell signaling. To...

EA - Morfologické obory a cytologie

  • 2009 - 2011
    • •
  • 3 500 tis. Kč
    • •
  • 3 500 tis. Kč
    • •
  • GA ČR
Projekt

Role of gamma- tubulin in the coordination of microtubule nucleation and cell division with the DNA damage response pathway in plants (GA15-11657S)

Gamma-tubulin is a conserved centrosomal microtubule nucleator, which in higher and chromatin. We began to identify resident proteins of gamma-tubulin complexes us to suggest that gamma-tubulin provides a platform for conve...

EB - Genetika a molekulární biologie

  • 2015 - 2019
    • •
  • 5 557 tis. Kč
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  • 5 557 tis. Kč
    • •
  • GA ČR
Projekt

Analysis and regulation of gamma-tubulin forms associated with membrane microdomains (GA204/05/2375)

y-Tubulin has an important role in microtubule nucleation. Recent data indicate that y-tubulin may have other essential, but as yet incompletely defined, functions. An association of y-tubulin with membranes was described a...

EA - Morfologické obory a cytologie

  • 2005 - 2007
    • •
  • 2 163 tis. Kč
    • •
  • 2 163 tis. Kč
    • •
  • GA ČR
Projekt

The role of Ran GTPases in microtubule nucleation and spindle organization in acentrosomal higher plant cells (GA204/07/1169)

-tubulin containing dispersed sites for microtubule nucleation in plants, part of gamma-tubulin waspresent in nuclei and with kinetochores. This project is focused of Arabidopsis homologues of RanBPM, RCC1 and homologue of Ran depen...

EB - Genetika a molekulární biologie

  • 2007 - 2011
    • •
  • 5 652 tis. Kč
    • •
  • 5 652 tis. Kč
    • •
  • GA ČR
Projekt

Microtubule organization in plant cells - development and application of in vitro assays for study of nucleation activity of isolated nuclei and chromosomes (GA204/99/D092)

spindle organization. We described recently that g-tubulin, an universal component, g-tubulin complexes were first characterized in plant cells in our laboratory. Herwe propose to develope in vitro assays as an approach to...

EB - Genetika a molekulární biologie

  • 1999 - 2002
    • •
  • 1 075 tis. Kč
    • •
  • 481 tis. Kč
    • •
  • GA ČR
Projekt

Gamma tubulin in Biomedicine and Biotechnology (ME 310)

In 1999 we will concentrate on preparative isolation of gamma tubulin from cells of cell lines and from the brain. The gamma tubulin asociate proteins will be identified. New hybridomas producing monoclonal antibodies against gamma ...

FP - Ostatní lékařské obory

  • 1998 - 2001
    • •
  • 1 383 tis. Kč
    • •
  • 333 tis. Kč
    • •
  • MŠMT
Projekt

Forms of gamma-tubulin and their interactions with proteins controlling cytokinesis, cell cycle and polarity. (IAA500200719)

Downregulation by RNAi showed previously that gamma-tubulin is essential revealed other as yet not defined roles for gamma-tubulin in cytokinesis and cell-tubulin bound to membranes and microtubules and their protein intera...

EF - Botanika

  • 2007 - 2011
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  • 4 596 tis. Kč
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  • 4 596 tis. Kč
    • •
  • AV ČR
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