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63 (0,064s)

Výsledek výzkumu

Comment on 'Topiramate maculopathy secondary to dose titration: first reported case'

Anotace : Authors believe, that ocular adverse effects of topiramate could be in its pharmacokinetics. The sudden changes in the plasma levels of topiramate should be avoided ....

FF - ORL, oftalmologie, stomatologie

  • 2016
  • Jx
  • Odkaz
Výsledek výzkumu

Monitoring topiramate concentrations at delivery and during lactation

To determine transplacental passage of topiramate and its transport to colostrum, mature maternal milk and breastfed infants, we examined data from 27 women treated with topiramate from 2004 to 2020....

Pharmacology and pharmacy

  • 2021
  • Jimp
  • Odkaz
Výsledek výzkumu

Motor performance and behavior of immature rats are not compromised by a high dose of topiramate

We studied the effects of topiramate on motor performance of 12- and 25-day-old rats using age-appropriate tests. Single high dose of topiramate does not compromise motor abilities and behavior of immature rats......

FH - Neurologie, neurochirurgie, neurovědy

  • 2005
  • Jx
Výsledek výzkumu

Topiramate induced metabolic acidosis and kidney stones - a case study

with topiramate induced metabolic acidosis and kidney stones.Materials and methods: The laboratory features of topiramate caused renal tubular acidosis in blood and urine during topiramate treatment, with correction of met...

Medical laboratory technology (including laboratory samples analysis; diagnostic technologies) (Biomaterials to be 2.9 [physical characteristics of living material as related to medical implants, devices, sensors])

  • 2017
  • Jimp
  • Odkaz
Výsledek výzkumu

Topiramate induced metabolic acidosis and kidney stones - a case study

with topiramate induced metabolic acidosis and kidney stones. Materials and methods: The laboratory features of topiramate caused renal tubular acidosis in blood and urine during topiramate treatment, with correction of...

Clinical medicine

  • 2017
  • Jimp
  • Odkaz
Výsledek výzkumu

Trends in neuroprotection research - the actual role of topiramate.

Trends in neuroprotection research - the actual role of topiramate.

FH - Neurologie, neurochirurgie, neurovědy

  • 2000
  • Jx
Výsledek výzkumu

Anticonvulsant action of topiramate against motor seizures in developing rats.

The anticonvulsant action of topiramate in developing rats was studied. It exhibits stable anticonvulsant action against the tonic phase of generalized tonic-clonic seizures throught development....

FH - Neurologie, neurochirurgie, neurovědy

  • 2000
  • Jx
Výsledek výzkumu

Pits of the DDisc and Maculopathy (Electroretinographic Study)

Patients with pits of the optic nerve and maculopathy exhibitis significant diminution of the ERG - b-waves, oscillatory potentials and photopic b-Waves....

FF - ORL, oftalmologie, stomatologie

  • 2002
  • Jx
Výsledek výzkumu

A Capillary GC Method Using Nitrogen Phosphorus Detection for Determination of Topiramate in Patients with Epilepsy

A new capillary gas chromatographic assay with nitrogen phosphorus detection for the determination of antiepileptic drug topiramate in the serum of epileptic patients was developed and validated. The sample procedure included a liquid-liquid...

FR - Farmakologie a lékárnická chemie

  • 2007
  • Jx
Výsledek výzkumu

The benefit of ERG during screening of chlooguine and hydroxychloroguine maculopathy

Derivates of chloroguine used in long-time treatment of rheumatic diseases cause clinically verified ireverzible maculopthy. The aim of the study was to evaluate indication of ERG examination for the reason of early diagnosis of cumulative maculo...

FF - ORL, oftalmologie, stomatologie

  • 2007
  • D
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