Filtry
Effects of Acyclic Nucleotide Analogues on cancer Cells.
Acyclic in vitro tests, nucleotide analogues, genotoxicity, apoptosis.
EB - Genetika a molekulární biologie
- 2000 •
- D
Rok uplatnění
D - Stať ve sborníku
Acyclic nucleoside and nucleotide analogues: chemical structure - biological activity relationship. (Bader prize lecture)
Bader prize lecture summarising projects dealing with synthesis and structure-activity relationship of acyclic nucleoside and nucleotide analogues, modified nucleobases and abbreviated NAD analogues....
CC - Organická chemie
- 2004 •
- Jx
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Antiviral acyclic nucleoside phosphonates structure activity studies
This review concerns acyclic nucleoside phosphonates (ANP) and describes the concept of the design of isopolar and isosteric nucleotide analogues resistant towards degradation by enzymes in vivo....
CC - Organická chemie
- 2006 •
- Jx
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Acyclic Nucleotide Analogues Suppress Growth and Induce Appoptosis in Human Leukemia Cell Lines
Acyclic nucleotide analogues perturb DNA replication by terminating the growing DNA chain...
FD - Onkologie a hematologie
- 1999 •
- Jx
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Involvement of adenosine A1 receptors in upregulation of nitric oxide by acyclic nucleotide analogues
acyclic nucleoside phosphonates as novel class of virostatics, the effect on NO and the role of adenosine receptors...
FR - Farmakologie a lékárnická chemie
- 2004 •
- Jx
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Cytokine-stimulatory effects of acyclic nucleotide analogues: extrapolation of immunopharmacological data from animal to human cells
Both qualitative and qantitative parameters of cytokine production stimulated by acyclic nucleotide analogues are very similar in mouse and human cells. The extent of cytokine production is tightly correlated with the enhan...
FR - Farmakologie a lékárnická chemie
- 2008 •
- C
Rok uplatnění
C - Kapitola v odborné knize
Compounds for preparation of enantiomeric nucleotide analogues with antiretroviral effect
2-O-Tetrahydropyranyl-1-LvO-propan-1,2-diol of formula XI and 2-O-tetrahydropyranyl-1-O-benzylpropan-1,2-diol of formula XII are useful as intermediates for preparation of acyclic nucleotide analogues, especially for prepar...
CC - Organická chemie
- 2004 •
- P
Rok uplatnění
P - Patent
Synthesis and biological activity of 2- and 6- C -substituted purine bases, nucleosides and acyclic nucleotide analogues.
Original scientific paper dealing with Synthesis and biological activity of 2- and 6- C -substituted purine bases, nucleosides and acyclic nucleotide analogues....
CC - Organická chemie
- 2000 •
- Jx
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Antiviral Acyclic Nucleotide Analogues.
Annotation not available...
CC - Organická chemie
- 1993 •
- D
Rok uplatnění
D - Stať ve sborníku
Cross-coupling reactions of 2-amino-6-halopurine derivatives with organometallic reagents leading to 6-alkylated purine acyclic nucleotide analogues.
Original scientific paper dealing with Cross-coupling reactions of 2-amino-6-halopurine derivatives with organometallic reagents leading to 6-alkylated purine acyclic nucleotide analogues....
CC - Organická chemie
- 1999 •
- D
Rok uplatnění
D - Stať ve sborníku
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