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Filtry

24 285 (0,117s)

Výsledek výzkumu

Circulating Cell-Free DNA Extraction from Liquid Biopsy for Cancer Research

biomarkers including circulating tumour DNA from liquid biopsy for diagnosis, prognosis better yields of circulating tumour DNA (P < 0.05). This DNA also had less. This could be chang...

Basic medicine

  • 2022
  • Jimp
  • Odkaz
Výsledek výzkumu

Circulating tumour DNA in patients with Hodgkin lymphoma

Circulating tumour DNA (ctDNA) is extracellular DNA which can be found in peripheral blood of patients suffering from malignancies. A liquid biopsy as a method of its non-invasive assessment might be potentially us...

Hematology

  • 2020
  • JSC
  • Odkaz
Výsledek výzkumu

Circulating tumour DNA in patients with Hodgkin lymphoma

Circulating tumour DNA (ctDNA) is extracellular DNA which can be found in peripheral blood of patients suffering from malignancies. A liquid biopsy as a method of its non-invasive assessment might be potentially us...

Hematology

  • 2020
  • JSC
  • Odkaz
Výsledek výzkumu

Tumor mutational burden from the molecular pathology point of view

for TMB evaluation are nowadays based on different modification of nextgeneration sequencing. New assays based on circulating tumor DNA (ctDNA) sequencing have been recently developed. TMB currently represents a v...

Pathology

  • 2019
  • Jost
  • Odkaz
Výsledek výzkumu

An update on circulating tumor DNA in patients with Hodgkin lymphoma

Circulating tumour DNA (ctDNA) is a type of extracellular circulating cell-free DNA (ccfDNA, cfDNA) released into the blood of cancer patients by apoptosis and necrosis of tumour cells. It represe...

Hematology

  • 2022
  • JSC
  • Odkaz
Výsledek výzkumu

High tumour mutational burden is associated with strong PD-L1 expression, HPV negativity, and worse survival in penile squamous cell carcinoma: an analysis of 165 cases

Penile squamous cell carcinoma (pSCC) is a rare tumour with a variable prognosis. More prognostic markers linked to mutational signatures and the tumour immune using formalin-fixed, paraffin-embedded tumour tissue, focusing...

Oncology

  • 2024
  • Jimp
  • Odkaz
Výsledek výzkumu

Early detection of colorectal cancer progression by monitoring of circulating tumour cells and free tumour DNA in patient blood and plasma samples.

Metastatic liver disease from colorectal cancer progression is a significant oncologic problem with hepatic resection as the main form of treatment. Non-invasive screening of molecular biomarkers may enable effective surgical intervention through an ...

FD - Onkologie a hematologie

  • 2010
  • O
Výsledek výzkumu

Comparison of whole exome sequencing and FoundationOne Heme sequencing panel as tools for precision oncology in paediatric patients with difficult-to-treat solid tumours

tumours. Methods: WES (both somatic and germline) in children with high-risk solid tumours was performed using TruSeq DNA Exome Kit, NextSeq 500/550 Mid Output Kit by an established pipeline. Tumour mutational bur...

Oncology

  • 2019
  • O
  • Odkaz
Výsledek výzkumu

Gene Mutations in Circulating Tumour DNA as a Diagnostic and Prognostic Marker in Head and Neck Cancer-A Systematic Review

(1) Background: Head and Neck Squamous Cell Carcinoma (HNSCC) is one of the most common malignancies globally. An early diagnosis of this disease is crucial, and the detection of gene mutations in circulating tumour DNA (ct...

Basic medicine

  • 2021
  • Jimp
  • Odkaz
Výsledek výzkumu

Utility of cell-free tumour DNA for post-surgical follow-up of colorectal cancer patients.

for monitoring of the disease are desirable. Tumour cell-free DNA (cfDNA) has been recently imaging CT, PET, MR, is frequently supported by the observation of tumour markers (CEA......

FD - Onkologie a hematologie

  • 2012
  • Jx
  • Odkaz
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