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Projekt

Molecular-genetic diagnosis of alpha-thalassemias and biochemical and molecular-genetic diagnosis of congenital hemolytic anemias associated with red blood cell enzymopathies (NT11208)

The aims of the proposed project is the study of the molecular pathophysiology of alpha-thalassemia and congenital hemolytic anemias resulting from enzymopathies of unknown etiology in patients from the Czech Republic. We propose: 1...

EB - Genetika a molekulární biologie

  • 2010 - 2013
  • 5 609 tis. Kč
  • 5 609 tis. Kč
  • MZ
Projekt

Cellular and molecular-genetic characterization of selected hereditary defects of erythropoiesis (NV19-07-00412)

This project aims to establish genetic background, etiology and pathogenesis of new cases of thalassemias, enzymopathies, erythrocyte membrane defects associated with hemolytic anemia, congenital dyserythropoietic anemia as...

Hematology

  • 2019 - 2023
  • 14 136 tis. Kč
  • 14 046 tis. Kč
  • MZ
Projekt

The evolution of advanced microangiopathic diabetic complications before and after simultaneous pancreas and kidney transplantation evaluated with progressive non-invasive methods (NW24-01-00138)

will compare the difference of the evolution of microangiopathic complications in subjects of pretransplant evaluation and treatment of diabetic microangiopathic lesions.......

Endocrinology and metabolism (including diabetes, hormones)

  • 2024 - 2027
  • 8 947 tis. Kč
  • 8 947 tis. Kč
  • MZ
Projekt

Significance of hepcidin in the diagnosis and treatment of anemia in children (NS9951)

Annotation 1. Inherited disorders of erythropoiesis and anemia of chronic disease (ACD) can cause morbidity and decreased quality of life. Assessing the level with currently used hematological parameters of anemia, evaluation of ben...

FG - Pediatrie

  • 2008 - 2011
  • 6 618 tis. Kč
  • 6 252 tis. Kč
  • MZ
Projekt

Late outcome of the infants and children with hemolytic-uremic syndrome. (NE4603)

This clinical study aims to evaluata the late outcome of patiens with hemolytic-uremic syndrome in childhood and to find out risk factor associated with untfavourable prognosis. A multicentric cooperative study is proposed to collect and eva...

FG - Pediatrie

  • 1998 - 2000
  • 1 038 tis. Kč
  • 862 tis. Kč
  • MZ
Projekt

New approaches to ciagnosis and treatment of hemolytic disorders (IZ4411)

Investigation of the role of red cell surface antigen expression and membrane protein composition changes in the pathogenesis and diabnosis of acquired hemolytic disorders. Investigation of the role of induced membrane lipid peroxidation in ...

FD - Onkologie a hematologie

  • 1997 - 1999
  • 5 814 tis. Kč
  • 4 319 tis. Kč
  • MZ
Projekt

Molecular-genetic characterization of selected cases with congenital anemia (NS10281)

The proposed project is dedicated to the molecular pathophysiology of congenital microcytic anemias in selected cases from Czech Republic. We will: 1. Perform cellular and molecular-genetic analysis of selected cases with congenital microcyt...

EB - Genetika a molekulární biologie

  • 2009 - 2011
  • 2 128 tis. Kč
  • 2 076 tis. Kč
  • MZ
Projekt

Bacteriological diagnostic medium employing the hemolytic interaction od Dermatophilus congolensis exosubstance. (IZ3707)

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 1996 - 1998
  • 237 tis. Kč
  • 237 tis. Kč
  • MZ
Projekt

Diagnostic culture medium for identification of bacterial species giving the hemolytic synergism with the equi factor of Rhodococcus equi. (IZ3714)

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 1996 - 1998
  • 227 tis. Kč
  • 227 tis. Kč
  • MZ
Projekt

Microbiological diagnostics and immunity of infection by Verotoxin - producing E.coli strains in children with hemolytic uremic syndrome. (IZ2063)

9F - 9

  • 1994 - 1996
  • 404 tis. Kč
  • 678 tis. Kč
  • MZ
  • 1 - 10 z 56