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167 382 (0,194s)

Výsledek výzkumu

Structural study of the Fox-1 RRM protein hydration reveals a role for key water molecules in RRM-RNA recognition

protein family. We report a 1.8 angstrom X-ray structure of the free Fox-1 containing) structure of the Fox1 protein/RNA complex for molecular dynamics (MD) analyses of the structured hydration. ...

Biochemistry and molecular biology

  • 2017
  • Jimp
  • Odkaz
Výsledek výzkumu

A systematic method for analysing the protein hydration structure of T4 lysozyme

A systematic method for the analysis of the hydration structure of proteins is demonstrated on the case study of lysozyme. The method utilises multiple structural data of the same protein deposited in the ...

CE - Biochemie

  • 2013
  • Jx
  • Odkaz
Výsledek výzkumu

Atlas of Protein Hydration

structures from the Protein Data Bank, as described in Biedermannova et al, Acta Cryst. DThe website provides information on the hydration of amino acid residues in different conformational states in X-ray crystal stru...

BO - Biofyzika

  • 2014
  • R
  • Odkaz
Výsledek výzkumu

Structure of the ordered hydration of amino acids in proteins: analysis of crystal structures

molecules near protein surfaces. Using a nonredundant set of 2818 protein crystal structures with a resolution of better than 1.8 angstrom, the extent and structure of the hydration shell of all 20 standa...

EB - Genetika a molekulární biologie

  • 2015
  • Jx
  • Odkaz
Výsledek výzkumu

WatAA: Atlas of Protein Hydration. Exploring synergies between data mining and ab initio calculations

of protein structure, dynamics and function. WatAA is a newly developed, web-based atlas of amino-acid hydration in proteins. The atlas provides information about the ordered first hydration shell of the ...

Computer sciences, information science, bioinformathics (hardware development to be 2.2, social aspect to be 5.8)

  • 2017
  • Jimp
  • Odkaz
Výsledek výzkumu

Calculation of hydration sites of amino-acid conformers

Program converts clusters of hydrated amino-acid conformers into electron density, calculates crystallographic structure factors, finds hydration site positions as peaks in the electron density and performs "refinement" of ...

BO - Biofyzika

  • 2014
  • R
  • Odkaz
Výsledek výzkumu

Calculation of clusters of hydrated amino-acid conformers

Program downoads specified set of structures from the Protein Data Bank (PDB), performs structure quality check, adds neighboring crystallographic cells, extracts water molecules in the vicinity of the selected protein<...

BO - Biofyzika

  • 2014
  • R
  • Odkaz
Výsledek výzkumu

Hydration of proteins and nucleic acids: Advances in experiment and theory. A review.

Background: Most biological processes involve water, and the interactions of biomolecules with water affect their structure, function and dynamics....

EB - Genetika a molekulární biologie

  • 2016
  • Jx
  • Odkaz
Výsledek výzkumu

Long-residency hydration, cation binding and dynamics of Loop E/Helix IV rRNA - L25 protein complex

Internal loops are common elements of RNA secondary structure. They often form binding sites for metals, proteins and other RNAs. To under-stand the effects of internal loops on RNA structure and function, we have carried o...

BO - Biofyzika

  • 2004
  • Jx
Výsledek výzkumu

Haloalkane dehalogenases as a subject for crystallographic studies

An integrated view of protein structure, solvation, dynamics, and function is emerging, where proteins are considered as dynamically active machines and internal protein motions are closely linked to function such ...

Biochemistry and molecular biology

  • 2017
  • O
  • Odkaz
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