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Výsledek výzkumu

Terbium-161 labelled thermoresponsive immunoactive polymer.

Sample of functional immunoactive thermoresponsive polymer labelled with 100 MBq of Tb-161.

Polymer science

  • 2023
  • Gfunk
Výsledek výzkumu

Terbium-161 production system

A production system for developed at CTU to allow reliable routine production of Tb-161 and its separation from target material, the Gd-160, and other radionuclidic impurities like Yb or Sm. The system was tested with approx. 40 mg of irradi...

Inorganic and nuclear chemistry

  • 2021
  • Gfunk
Výsledek výzkumu

Terbium-161 production and quality control

Terbium-161 is a promising radionuclide for medicinal use. Its physical terbium-161 can be prepared by irradiating Gd in form of oxide or nitrate highly enriched with 160Gd in nuclear reactor. Terbium-...

Inorganic and nuclear chemistry

  • 2024
  • O
  • Odkaz
Výsledek výzkumu

Separation of terbium from a gadolinium target for the purpose of preparation of 161Tb-labeled radiopharmaceuticals

Terbium-161 is a perspective radionuclide with a potential use in nuclear the terbium from the target. In this work, the cation exchange chromatography on Dowex for the seaparation of Terbium from the target materi...

Inorganic and nuclear chemistry

  • 2021
  • O
Výsledek výzkumu

Terbium-161 labelled thermoresponsive polymer

The radiolabelled thermoresponsive polymer pNIPAM-DOTA with 161Tb was prepared. The procedure involved radiolabelling step, separation of the labelled polymer from unreacted Tb-161 and its purification. Final radiolabelling yield was 85,9 %,...

Inorganic and nuclear chemistry

  • 2023
  • Gfunk
Výsledek výzkumu

Separation of terbium-161 from gadolinium target irradiated in nuclear reactor

Terbium-161 is one of the perspective radionuclides with a potential use increases its potential therapeutic efficacy. Terbium-161 can be prepared as no carrier reactor. After irradiation, it is necessary to separa...

Inorganic and nuclear chemistry

  • 2022
  • O
Výsledek výzkumu

Separation of Tb, Gd and Dy for the purpose of preparation of radiopharmaceuticals labelled with 161Tb

Terbium-161 is a perspective radionuclide with a potential use in nuclear medicine thanks to its ideal energy of beta radiation and half-life. Terbium-161 can be prepared by irradiation of enriched 160Gd target in ...

Inorganic and nuclear chemistry

  • 2021
  • D
  • Odkaz
Výsledek výzkumu

Pure Terbium-161 sample - 1 GBq

A sample of 1 GBq of pure Tb-161 was prepared by neutron irradiation of highly enriched Gd-160 and subsequent target dissolution and separation on a chromatographic as eluent. After separation, Tb-161 containing fractions were purif...

Inorganic and nuclear chemistry

  • 2021
  • Gfunk
Výsledek výzkumu

Pure Terbium-161 sample - 1 GBq

A sample of 1 GBq of pure Tb-161 was prepared by neutron irradiation of highly enriched Gd-160 and subsequent target dissolution and separation on a chromatographic as eluent. After separation, Tb-161 containing fractions were purif...

Inorganic and nuclear chemistry

  • 2021
  • Gfunk
Výsledek výzkumu

Pure Terbium-161 sample - 5 GBq

A sample of 5 GBq of pure Tb-161 was prepared by neutron irradiation of highly enriched Gd-160 and subsequent target dissolution and separation on a chromatographic separation, Tb-161 containing fractions were purified on another Do...

Inorganic and nuclear chemistry

  • 2021
  • Gfunk
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