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Projekt

Analysis of interaction between Leishmania major and macrophages of susceptible and resistant mouse strains. (GP14-35944P)

cellular compartment for Leishmania are macrophages. We and others have shown that macrophages of different inbred strains differ in permissiveness for Leishmania infection. The aim of the project is to characterize the molecular b...

EB - Genetika a molekulární biologie

  • 2014 - 2017
  • 1 380 tis. Kč
  • 1 380 tis. Kč
  • GA ČR
Projekt

The role of macrophages in emergency lipid mobilization (GA23-06133S)

Infiltration of the liver by macrophages and subsequent cytokine-induced, it has recently been found that macrophages also infiltrate the liver during states hypothesize that macrophage-induced hepatic insulin resistance re...

Immunology

  • 2023 - 2025
  • 9 753 tis. Kč
  • 9 753 tis. Kč
  • GA ČR
Projekt

The effects of a surgical procedure on local peritoneal imunity (NS9649)

of the peritoneal macrophages after laparoscopic and laparotomic procedures. Their activity part will compare the activity of the macrophages 24 and 72 hours after, the activity of peripheral macrophages will be determined...

FJ - Chirurgie včetně transplantologie

  • 2008 - 2011
  • 3 417 tis. Kč
  • 3 369 tis. Kč
  • MZ
Projekt

Phenotypic response of macrophages in adipose tissue remodeling in Drosophila – possible model for obesity-associated diseases (GA20-14030S)

tissue contains hypertrophic adipocytes surrounded by macrophages forming crown-like structures. Although macrophages primarily take up lipids to protect the organism from their phenotypic response substantially so that lipid-laden...

Cell biology

  • 2020 - 2023
  • 6 115 tis. Kč
  • 6 115 tis. Kč
  • GA ČR
Projekt

How does vaccinia virus induce macrophage apoptosis? Role of nitric oxide and cytokines (GA310/96/0514)

Phagocytic cells of the monocyte/ macrophage cell lineage play a decisive role viruses replication in macrophages. Our data show, that IFNy- mediated inhibition of viruses replication in macrophages. Our data show, that IFN...

EE - Mikrobiologie, virologie

  • 1996 - 1998
  • 2 428 tis. Kč
  • 1 990 tis. Kč
  • GA ČR
Projekt

Identification and functional analysis of different macrophage and neutrophil subpopulations (LD15069)

. monocytes/macrophages and neutrophils) have been described quite recently. Importantly. Therefore, the objective of present project is to identify specific monocyte/macrophage and development of general protocols for monocyte/...

EC - Imunologie

  • 2015 - 2017
  • 1 628 tis. Kč
  • 1 628 tis. Kč
  • MŠMT
Projekt

Identification of differentially expressed genes during macrophage activation in the horse (GP523/02/D126)

Identification of differentially expressed genes during macrophage activation in the horse. Horse macrophages will be isolated and in vitro stimulated by LPS (R.equi, BCG). Differentially expressed genes will be identified using sup...

GI - Šlechtění a plemenářství hospodářských zvířat

  • 2002 - 2005
  • 693 tis. Kč
  • 693 tis. Kč
  • GA ČR
Projekt

Mucosal tolerance in a murine model of corneal transplantation (ME 300)

Study of cellular and molecular mechanisms of rejection and tolerance of orthotopic corneal allografts in the experimental murine model. Study of potencial of the mucosal tolerance as a strategy for suppression of the immunological rejection...

EC - Imunologie

  • 1998 - 2000
  • 2 631 tis. Kč
  • 935 tis. Kč
  • MŠMT
Projekt

The interplay of arterial wall and perivascular adipose tissue in the initiation of atherogenesis (NV17-28103A)

The relationship of the content and proportion of pro-inflammatory M1 and anti-inflammatory M2 macrophages between the human artery and adjacent perivascular adipose living kidney donors - women). The proportion of the macrophage su...

FA - Kardiovaskulární nemoci včetně kardiochirurgie

  • 2017 - 2020
  • 4 229 tis. Kč
  • 4 229 tis. Kč
  • MZ
Projekt

Macrophage polarization and the fatty acid spectrum of cell membrane phospholipids of adipose tissue (NU20-01-00022)

We have recently published that the proportion of pro-inflammatory macrophages of human adipose tissue (CD14+, CD16+, CD36+++) correlates positively with the main fatty acids. The aim of this project is to establish whether macrophage

Endocrinology and metabolism (including diabetes, hormones)

  • 2020 - 2023
  • 4 242 tis. Kč
  • 4 242 tis. Kč
  • MZ
  • 1 - 10 z 160