Filtry
Inverse correlation between TP53 gene status and PD-L1 protein levels in a melanoma cell model depends on an IRF1/SOX10 regulatory axis
that p53 loss influences the recently discovered SOX10/IRF1 regulatory axis-regulation of immune signaling by both transcription factors. However, IRF1/PD-L1 regulation by p53 activation revealed complicated regulatory mec...
Biochemistry and molecular biology
- 2024 •
- Jimp •
- Odkaz
Rok uplatnění
Jimp - Článek v periodiku v databázi Web of Science
Výsledek na webu
AVIAN INTERFERON REGULATORY FACTORS (ALMOST) RESOLVED
Interferon regulatory factors (IRFs) are transcription factors that play which is together with other type I interferons responsible for forming ISGF3 in the nucleus with interferon-stimulat...
Virology
- 2024 •
- O •
- Odkaz
Rok uplatnění
O - Ostatní výsledky
Výsledek na webu
Primer set for detection of single nucleotide polymorphism in the interferon gamma (IFNG) gene in sheep
The solution relates to a kit for the detection of genetic point polymorphism in the signal peptide region, the promoter and the regulatory region of exons 1, 2 and 3 in the interferon gamma gene (IFNG) in sheep. T...
Husbandry
- 2024 •
- Fuzit
Rok uplatnění
Fuzit - Užitný vzor
DISCOVERY OF NOVEL AVIAN INTERFERON REGULATORY FACTORS
Interferon regulatory factors (IRFs) are transcription factors that play which is together with other type I interferons responsible for expression of interferon-stimulated genes (ISGs) ...
Virology
- 2023 •
- O •
- Odkaz
Rok uplatnění
O - Ostatní výsledky
Výsledek na webu
Identification of genetic elements in metabolism by high-throughput mouse phenotyping
Metabolic diseases are a worldwide problem but the underlying genetic factors and their relevance to metabolic disease remain incompletely understood. Genome-wide research genes are associated with metabolic
Other biological topics
- 2018 •
- Jimp •
- Odkaz
Rok uplatnění
Jimp - Článek v periodiku v databázi Web of Science
Výsledek na webu
Distinct Roles of Kaposi's Sarcoma-Associated Herpesvirus-Encoded Viral Interferon Regulatory Factors in Inflammatory Response and Cancer
-encodedhomologues of cellular interferon regulatory factors (IRFs)-viral IRF1 (vIRF1) to vIRF4...
EE - Mikrobiologie, virologie
- 2013 •
- Jx •
- Odkaz
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Výsledek na webu
Vaccinia Virus Expressing Interferon Regulatory Factor 3 Induces Higher Protective Immune Responses against Lethal Poxvirus Challenge in Atopic Organism
interferon is compromised, while VACV specifically inhibits the phosphorylation of the Interferon Regulatory Factor 3 (IRF-3) and expression of interferons. To overcome of serious complications in atopic ...
Technologies involving the manipulation of cells, tissues, organs or the whole organism (assisted reproduction)
- 2021 •
- Jimp •
- Odkaz
Rok uplatnění
Jimp - Článek v periodiku v databázi Web of Science
Výsledek na webu
A multiprotein binding interface in an intrinsically disordered region of the tumor suppressor protein interferon regulatory factor-1
The interferon-regulated transcription factor and tumor suppressor protein IRF-1 is predicted to be largely disordered outside of the DNA-binding domain. One, relatively few IRF-1-interacting proteins have been des...
EB - Genetika a molekulární biologie
- 2011 •
- Jx •
- Odkaz
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Výsledek na webu
Metabolic and Proliferative State of Vascular Adventitial Fibroblasts in Pulmonary Hypertension Is Regulated Through a MicroRNA-124/PTBP1 (Polypyrimidine Tract Binding Protein 1)/Pyruvate Kinase
We have uncovered regulatory pathway responsible for metabolic changes in human and bovine hypertensive pulmonary arterial walls leading to hyperproliferation, apoptosis-resistance and proinflammation....
Respiratory systems
- 2017 •
- Jimp •
- Odkaz
Rok uplatnění
Jimp - Článek v periodiku v databázi Web of Science
Výsledek na webu
A multiprotein binding interface in an intrinsically disordered region of the tumour suppressor protein Interferon Regulatory Factor-1
The interferon-regulated transcription factor IRF-1 is predicted to be largely of IRF-1 led us to ask whether this region might be employed more widely by regulators of IRF-1 function. Here we describe the...
FD - Onkologie a hematologie
- 2011 •
- Jx •
- Odkaz
Rok uplatnění
Jx - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
Výsledek na webu
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