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Výsledek výzkumu

Neutrophil extracellular traps - immune system's safety net

Neutrophil extracellular traps (NETs) are beneficial antimicrobial defense structures. They are produced by activated neutrophils and consist of chromatin, granular and cytoplasmic proteins. They resemble nets and ...

Immunology

  • 2017
  • Jost
  • Odkaz
Výsledek výzkumu

Frontline Science: Aggregated neutrophil extracellular traps prevent inflammation on the neutrophil-rich ocular surface

revealed the presence of viable neutrophils, bacteria, epithelial cells, and particles, aggregated by neutrophil extracellular traps. We observed that in the evening, during eye. These conditions favored the forma...

Rheumatology

  • 2019
  • Jimp
  • Odkaz
Výsledek výzkumu

Frontline Science: Aggregated neutrophil extracellular traps prevent inflammation on the neutrophil-rich ocular surface

revealed the presence of viable neutrophils, bacteria, epithelial cells, and particles, aggregated by neutrophil extracellular traps. We observed that in the evening, during eye. These conditions favored the forma...

Rheumatology

  • 2019
  • Jimp
  • Odkaz
Výsledek výzkumu

Neutrophil Extracellular Traps Entrap and Kill Borrelia burgdorferi Sensu Stricto Spirochetes and Are Not Affected by Ixodes ricinus Tick Saliva

of neutrophils. The neutrophil extracellular trap (NET) consists in the extrusion of the neutrophil's own DNA, forming traps that can retain and kill bacteria. The production of infestation, ...

EC - Imunologie

  • 2012
  • Jx
  • Odkaz
Výsledek výzkumu

Neutrophil extracellular traps in type 1 diabetes

the underlying mechanisms is crucial. Here, we focus on neutrophils and their products called neutrophil extracellular traps (NETs). NET structures are predominantly composed of neutrophil DNA and antimic...

Endocrinology and metabolism (including diabetes, hormones)

  • 2021
  • JSC
  • Odkaz
Výsledek výzkumu

Aggregated neutrophil extracellular traps resolve inflammation by proteolysis of cytokines and chemokines and protection from antiproteases

we investigated neutrophil extracellular trap (NET)-associated aggregation neutrophil extracellular traps resolve inflammation by proteolysis of cytokinesPapillon-Lefevre syndrome (PLS) is charac...

Rheumatology

  • 2019
  • Jimp
  • Odkaz
Výsledek výzkumu

Treatment with DNases rescues hidden neutrophil elastase from aggregated NETs

The release of neutrophil extracellular traps (NETs) is one of the weapons neutrophils have in their armory. NETs consist of extracellular chromatin fibers decorated protease neutrophil elastase (...

Rheumatology

  • 2019
  • Jimp
  • Odkaz
Výsledek výzkumu

Neutrophil extracellular traps characterize caseating granulomas

of this study was to determine neutrophil activation and circulatory neutrophil extracellular trap (NET) formation in various types of TB. Sera from TB patients (n = 91 poses a serious challenge to public health. ...

Biological sciences

  • 2024
  • Jimp
  • Odkaz
Výsledek výzkumu

NETosis provides the link between activation of neutrophils on hemodialysis membrane and comorbidities in dialyzed patients

Introduction: Neutrophil extracellular traps (NETs) are formed by activated neutrophils during the process of NETosis in which the nuclear material is released into extracellular space, including DNA molec...

Urology and nephrology

  • 2017
  • Jimp
  • Odkaz
Výsledek výzkumu

S100A11 (calgizzarin) is released via NETosis in rheumatoid arthritis (RA) and stimulates IL-6 and TNF secretion by neutrophils

autoimmune diseases, including rheumatoid arthritis (RA). Neutrophil extracellular traps by neutrophils in the RA synovial tissue was assessed. Neutrophils isolated from peripheral by immunofluorescence. ...

Rheumatology

  • 2021
  • Jimp
  • Odkaz
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